Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
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Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Score
Swit_4725Aminotransferase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent enzymes; aminotransferase, class I and II. (388 aa)    
Predicted Functional Partners:
dapD
TIGRFAM: 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase; Belongs to the transferase hexapeptide repeat family.
  
 
 0.912
argD
TIGRFAM: acetylornithine and succinylornithine aminotransferase; PFAM: aminotransferase class-III; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
    
 0.908
dapE
Succinyldiaminopimelate desuccinylase; Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls; Belongs to the peptidase M20A family. DapE subfamily.
    
 0.908
Swit_4726
Multi-sensor hybrid histidine kinase; PFAM: response regulator receiver; ATP-binding region, ATPase domain protein domain protein; histidine kinase A domain protein domain protein; CHASE3 domain protein.
     
 0.588
Swit_0265
PFAM: glutamine amidotransferase, class-II; glutamate synthase, alpha subunit domain protein; ferredoxin-dependent glutamate synthase; glutamate synthase.
  
  
 0.504
Swit_0657
PFAM: glutamine amidotransferase, class-II; glutamate synthase, alpha subunit domain protein; ferredoxin-dependent glutamate synthase; glutamate synthase.
  
  
 0.504
ligA
DNA ligase, NAD-dependent; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.
  
    0.480
Swit_0771
Molecular chaperone-like protein.
 
 
 
 0.455
Swit_1904
Malate dehydrogenase (oxaloacetate-decarboxylating) (NADP(+))., Phosphate acetyltransferase; PFAM: phosphate acetyl/butaryl transferase; malic enzyme domain protein; malic enzyme, NAD-binding.
  
 
 0.430
Swit_2760
Malate dehydrogenase (oxaloacetate-decarboxylating) (NADP(+)); Phosphate acetyltransferase; PFAM: phosphate acetyl/butaryl transferase; malic enzyme domain protein; malic enzyme, NAD-binding.
  
 
 0.430
Your Current Organism:
Sphingomonas wittichii
NCBI taxonomy Id: 392499
Other names: S. wittichii RW1, Sphingomonas sp. RW1, Sphingomonas wittichii DSM 6014, Sphingomonas wittichii RW1, Sphingomonas wittichii str. RW1, Sphingomonas wittichii strain RW1
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