Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Swit_4793PFAM: protein of unknown function DUF470; protein of unknown function DUF471; protein of unknown function DUF472. (872 aa)    
Predicted Functional Partners:
Swit_4801
Type IV secretory pathway VirJ component-like protein.
 
  
 0.944
Swit_4800
PFAM: virulence factor family protein.
 
  
 0.915
Swit_4794
Uncharacterized protein.
       0.870
Swit_4796
PFAM: protein of unknown function DUF1003.
 
     0.725
tilS
tRNA(Ile)-lysidine synthetase; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. Belongs to the tRNA(Ile)-lysidine synthase family.
     
 0.633
Swit_4799
Integral membrane sensor signal transduction histidine kinase; PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase, HAMP region domain protein; histidine kinase A domain protein domain protein.
 
  
 0.606
Swit_2751
PFAM: glycosyl transferase, family 2; polysaccharide deacetylase; chitin synthase; SMART: chitinase II.
  
  
 0.577
Swit_1177
S-formylglutathione hydrolase; Serine hydrolase involved in the detoxification of formaldehyde.
     
 0.564
Swit_1916
PFAM: Endonuclease/exonuclease/phosphatase.
 
  
 0.554
Swit_4795
Hypothetical protein.
       0.535
Your Current Organism:
Sphingomonas wittichii
NCBI taxonomy Id: 392499
Other names: S. wittichii RW1, Sphingomonas sp. RW1, Sphingomonas wittichii DSM 6014, Sphingomonas wittichii RW1, Sphingomonas wittichii str. RW1, Sphingomonas wittichii strain RW1
Server load: low (8%) [HD]