Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
Swit_4800PFAM: virulence factor family protein. (492 aa)    
Predicted Functional Partners:
Swit_4793
PFAM: protein of unknown function DUF470; protein of unknown function DUF471; protein of unknown function DUF472.
 
  
 0.915
Swit_4801
Type IV secretory pathway VirJ component-like protein.
 
    
0.833
Swit_4799
Integral membrane sensor signal transduction histidine kinase; PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase, HAMP region domain protein; histidine kinase A domain protein domain protein.
     
 0.553
Swit_4796
PFAM: protein of unknown function DUF1003.
       0.544
Swit_4797
SMART: PDZ/DHR/GLGF domain protein.
       0.542
Swit_4798
Two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein.
       0.542
Your Current Organism:
Sphingomonas wittichii
NCBI taxonomy Id: 392499
Other names: S. wittichii RW1, Sphingomonas sp. RW1, Sphingomonas wittichii DSM 6014, Sphingomonas wittichii RW1, Sphingomonas wittichii str. RW1, Sphingomonas wittichii strain RW1
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