Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Swit_4819PFAM: MscS Mechanosensitive ion channel. (392 aa)    
Predicted Functional Partners:
Swit_4820
PFAM: O-antigen polymerase.
       0.773
Swit_0454
PFAM: TrkA-N domain protein; sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family.
 
  
 0.572
Swit_0003
PFAM: TrkA-N domain protein; sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family.
 
  
 0.537
Swit_0590
PFAM: cyclic nucleotide-binding; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; 4Fe-4S ferredoxin, iron-sulfur binding domain protein.
 
  
 0.474
Swit_4821
PFAM: glycosyl transferase, group 1.
     
 0.468
Swit_0786
PFAM: binding-protein-dependent transport systems inner membrane component; Substrate-binding region of ABC-type glycine betaine transport system.
  
  
 0.466
Swit_1509
PFAM: 17 kDa surface antigen.
 
    0.452
Swit_0455
TIGRFAM: potassium efflux system protein; PFAM: TrkA-N domain protein; sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family.
  
  
 0.450
Your Current Organism:
Sphingomonas wittichii
NCBI taxonomy Id: 392499
Other names: S. wittichii RW1, Sphingomonas sp. RW1, Sphingomonas wittichii DSM 6014, Sphingomonas wittichii RW1, Sphingomonas wittichii str. RW1, Sphingomonas wittichii strain RW1
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