Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
Swit_4849PFAM: Tetratricopeptide TPR_4. (407 aa)    
Predicted Functional Partners:
Swit_4850
Hypothetical protein.
 
     0.928
Swit_4847
PFAM: protein of unknown function DUF899, thioredoxin family protein.
 
     0.872
Swit_4488
PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; protein of unknown function DUF899, thioredoxin family protein.
 
     0.753
Swit_1700
Signal transduction histidine kinase, nitrogen specific, NtrB; TIGRFAM: PAS sensor protein; PFAM: response regulator receiver; ATP-binding region, ATPase domain protein domain protein; histidine kinase A domain protein domain protein; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein.
  
 
 0.720
Swit_4848
Hypothetical protein.
       0.618
Swit_4740
Integral membrane sensor signal transduction histidine kinase; PFAM: ATP-binding region, ATPase domain protein domain protein; CHASE2 domain protein.
 
 
 0.551
Swit_4629
PFAM: protein of unknown function DUF886.
  
     0.493
Swit_0699
Signal transduction histidine kinase; PFAM: response regulator receiver; ATP-binding region, ATPase domain protein domain protein; histidine kinase A domain protein domain protein.
  
 
 0.492
Swit_3156
Transcriptional regulator, MarR family; PFAM: regulatory protein, MarR.
  
  
 0.480
Swit_2540
PFAM: response regulator receiver.
  
 
 0.454
Your Current Organism:
Sphingomonas wittichii
NCBI taxonomy Id: 392499
Other names: S. wittichii RW1, Sphingomonas sp. RW1, Sphingomonas wittichii DSM 6014, Sphingomonas wittichii RW1, Sphingomonas wittichii str. RW1, Sphingomonas wittichii strain RW1
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