Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Swoo_0014KEGG: sse:Ssed_0016 DNA-3-methyladenine glycosylase I; TIGRFAM: DNA-3-methyladenine glycosylase I; PFAM: methyladenine glycosylase. (194 aa)    
Predicted Functional Partners:
Swoo_1744
methylated-DNA--protein-cysteine methyltransferase; Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
   
 0.745
Swoo_4762
PFAM: Excinuclease ABC C subunit domain protein; KEGG: sse:Ssed_4370 excinuclease ABC, C subunit domain protein.
      0.699
glyQ
KEGG: spl:Spea_0007 glycyl-tRNA synthetase, alpha subunit; TIGRFAM: glycyl-tRNA synthetase, alpha subunit; PFAM: glycyl-tRNA synthetase alpha subunit.
       0.604
glyS
KEGG: spl:Spea_0006 glycyl-tRNA synthetase, beta subunit; TIGRFAM: glycyl-tRNA synthetase, beta subunit.
       0.599
selD
Selenide, water dikinase; Synthesizes selenophosphate from selenide and ATP.
     
 0.586
pepQ
Peptidase M24; Splits dipeptides with a prolyl residue in the C-terminal position.
      
 0.582
Swoo_1743
PFAM: helix-turn-helix- domain containing protein AraC type; HhH-GPD family protein; Ada metal-binding domain protein; AlkA domain protein; KEGG: sse:Ssed_2904 transcriptional regulator, AraC family.
     
 0.482
Your Current Organism:
Shewanella woodyi
NCBI taxonomy Id: 392500
Other names: S. woodyi ATCC 51908, Shewanella woodyi ATCC 51908, Shewanella woodyi str. ATCC 51908, Shewanella woodyi strain ATCC 51908
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