Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
kdkALipopolysaccharide kinase; Catalyzes the ATP-dependent phosphorylation of the 3-deoxy-D- manno-octulosonic acid (Kdo) residue in Kdo-lipid IV(A) at the 4-OH position; Belongs to the protein kinase superfamily. KdkA/RfaP family. (252 aa)    
Predicted Functional Partners:
Swoo_0067
Three-deoxy-D-manno-octulosonic-acid transferase domain protein; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family.
   
 0.991
Swoo_0070
PFAM: glycosyl transferase family 9; KEGG: slo:Shew_3702 glycosyl transferase, family 9.
 
 
 
 0.906
nuoC
NADH dehydrogenase I, D subunit; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; In the N-terminal section; belongs to the complex I 30 kDa subunit family.
    
 0.882
htpG
Heat shock protein Hsp90; Molecular chaperone. Has ATPase activity.
    
 0.838
Swoo_1746
PFAM: Dual specificity protein phosphatase; KEGG: sse:Ssed_2901 dual specificity protein phosphatase.
    
 0.836
Swoo_2369
Putative signal transduction protein with EFhand domain; PFAM: Calcium-binding EF-hand-containing protein; KEGG: mxa:MXAN_2316 EF hand domain protein.
  
 
 0.809
Swoo_1878
PFAM: protein kinase; Protein phosphatase 2C-like; SMART: tyrosine protein kinase; protein phosphatase 2C domain protein; serine/threonine protein kinase; KEGG: sse:Ssed_2762 serine/threonine protein kinase.
   
 0.797
Swoo_2627
PFAM: Protein phosphatase 2C-like; SMART: protein phosphatase 2C domain protein; serine/threonine protein kinase; KEGG: sse:Ssed_1963 serine/threonine protein kinase.
   
 0.797
Swoo_1012
Bis(5'-nucleosyl)-tetraphosphatase (symmetrical); Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP; Belongs to the Ap4A hydrolase family.
    
 0.772
Swoo_0967
PFAM: WD-40 repeat protein; KEGG: sse:Ssed_0917 WD-40 repeat protein.
   
 0.770
Your Current Organism:
Shewanella woodyi
NCBI taxonomy Id: 392500
Other names: S. woodyi ATCC 51908, Shewanella woodyi ATCC 51908, Shewanella woodyi str. ATCC 51908, Shewanella woodyi strain ATCC 51908
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