Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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nfuAIscR-regulated protein YhgI; Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins. (192 aa)    
Predicted Functional Partners:
Swoo_1777
FeS cluster assembly scaffold IscU; A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters.
  
 0.979
Swoo_0566
PFAM: aminotransferase class V; beta-lactamase domain protein; SMART: Rhodanese domain protein; KEGG: slo:Shew_3354 aminotransferase, class V.
  
 0.969
iscS
Cysteine desulfurase IscS; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
  
 0.944
Swoo_2160
TIGRFAM: glutaredoxin-like protein; PFAM: glutaredoxin; KEGG: sse:Ssed_2444 glutaredoxin-like protein; Belongs to the glutaredoxin family. Monothiol subfamily.
  
 0.887
Swoo_0217
PFAM: ferredoxin; oxidoreductase FAD/NAD(P)-binding domain protein; Oxidoreductase FAD-binding domain protein; Ferric reductase NAD binding; KEGG: mmw:Mmwyl1_3091 phenylacetate-CoA oxygenase/reductase, PaaK subunit.
  
 0.878
Swoo_1261
PFAM: ferredoxin; oxidoreductase FAD/NAD(P)-binding domain protein; Oxidoreductase FAD-binding domain protein; KEGG: sse:Ssed_1166 oxidoreductase FAD-binding domain protein.
  
 0.878
Swoo_0575
PFAM: ferredoxin; oxidoreductase FAD/NAD(P)-binding domain protein; Oxidoreductase FAD-binding domain protein; KEGG: mca:MCA2508 oxygenase, putative.
  
 0.864
Swoo_2756
PFAM: ferredoxin; oxidoreductase FAD/NAD(P)-binding domain protein; Oxidoreductase FAD-binding domain protein; KEGG: sse:Ssed_1832 oxidoreductase FAD-binding domain protein.
  
 0.864
Swoo_0510
TIGRFAM: succinate dehydrogenase and fumarate reductase iron-sulfur protein; PFAM: ferredoxin; KEGG: sse:Ssed_4113 succinate dehydrogenase; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
  
 0.847
Swoo_1836
TIGRFAM: succinate dehydrogenase and fumarate reductase iron-sulfur protein; KEGG: sse:Ssed_2815 succinate dehydrogenase (ubiquinone); Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
  
 0.847
Your Current Organism:
Shewanella woodyi
NCBI taxonomy Id: 392500
Other names: S. woodyi ATCC 51908, Shewanella woodyi ATCC 51908, Shewanella woodyi str. ATCC 51908, Shewanella woodyi strain ATCC 51908
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