STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Swoo_0271KEGG: spl:Spea_3943 conserved hypothetical protein. (523 aa)    
Predicted Functional Partners:
Swoo_0270
Radical SAM domain protein; PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; Radical SAM domain protein; KEGG: spl:Spea_3944 radical SAM domain protein.
 
  
 0.925
queE
Radical activating enzyme; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
  
 
 0.709
Swoo_3048
Anaerobic ribonucleoside-triphosphate reductase activating protein; Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.
  
 
 0.709
Swoo_2948
PFAM: protein of unknown function DUF1097; KEGG: sse:Ssed_1663 hypothetical protein.
  
     0.589
Swoo_1221
PFAM: glutamine amidotransferase class-II; glutamate synthase alpha subunit domain protein; ferredoxin-dependent glutamate synthase; glutamate synthase; KEGG: sse:Ssed_1126 glutamate synthase (ferredoxin).
      
 0.576
Swoo_4889
PFAM: protein of unknown function DUF1063; KEGG: shn:Shewana3_2972 protein of unknown function DUF1063; Belongs to the UPF0597 family.
  
   
 0.572
Swoo_1445
PFAM: PfkB domain protein; Helix-turn-helix type 11 domain protein; KEGG: sse:Ssed_1351 PfkB domain protein.
  
     0.566
Swoo_1767
KEGG: sse:Ssed_2881 hypothetical protein.
  
     0.565
Swoo_0240
KEGG: spl:Spea_3967 formate-dependent nitrite reductase.
  
    0.553
grpE
GrpE protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...]
  
    0.508
Your Current Organism:
Shewanella woodyi
NCBI taxonomy Id: 392500
Other names: S. woodyi ATCC 51908, Shewanella woodyi ATCC 51908, Shewanella woodyi str. ATCC 51908, Shewanella woodyi strain ATCC 51908
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