Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
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[Homology]
Score
Swoo_0316PFAM: N-acetylmuramoyl-L-alanine amidase family 2; KEGG: slo:Shew_3434 N-acetylmuramyl-L-alanine amidase, negative regulator of AmpC, AmpD. (190 aa)    
Predicted Functional Partners:
Swoo_0317
KEGG: sse:Ssed_0429 signaling modulator of AmpD, AmpE.
 
  
 0.835
Swoo_0315
KEGG: sse:Ssed_0427 nicotinate-nucleotide diphosphorylase (carboxylating); TIGRFAM: nicotinate-nucleotide pyrophosphorylase; PFAM: Quinolinate phosphoribosyl transferase; Belongs to the NadC/ModD family.
  
  
 0.707
anmK
Protein of unknown function UPF0075; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family.
  
   
 0.666
mpl
UDP-N-acetylmuramate; Reutilizes the intact tripeptide L-alanyl-gamma-D-glutamyl- meso-diaminopimelate by linking it to UDP-N-acetylmuramate. Belongs to the MurCDEF family. Mpl subfamily.
  
   
 0.662
nagZ
Glycoside hydrolase family 3 domain protein; Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide- linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N- acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides. Belongs to the glycosyl hydrolase 3 family. NagZ subfamily.
 
   
 0.640
Swoo_3644
PFAM: major facilitator superfamily MFS_1; KEGG: sse:Ssed_3442 major facilitator superfamily MFS_1.
 
   
 0.635
Swoo_4173
N-acetylmuramoyl-L-alanine amidase; PFAM: Peptidoglycan-binding LysM; cell wall hydrolase/autolysin; KEGG: sse:Ssed_0794 N-acetylmuramoyl-L-alanine amidase.
  
  
 0.589
Swoo_2118
PFAM: beta-lactamase; KEGG: sse:Ssed_2498 beta-lactamase.
      
 0.582
ftsI
Peptidoglycan glycosyltransferase; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum.
     
 0.570
Swoo_0318
PFAM: regulatory protein GntR HTH; GntR domain protein; KEGG: sse:Ssed_0430 regulatory protein GntR, HTH.
       0.502
Your Current Organism:
Shewanella woodyi
NCBI taxonomy Id: 392500
Other names: S. woodyi ATCC 51908, Shewanella woodyi ATCC 51908, Shewanella woodyi str. ATCC 51908, Shewanella woodyi strain ATCC 51908
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