STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Swoo_0481PFAM: protein of unknown function DUF513 hemX; KEGG: sse:Ssed_4135 protein of unknown function DUF513, HemX. (383 aa)    
Predicted Functional Partners:
Swoo_0482
Uroporphyrinogen III synthase HEM4; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.
 
 0.983
Swoo_0480
PFAM: HemY domain protein; KEGG: sse:Ssed_4136 HemY domain protein.
 
  
 0.977
hemE
Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
    
 0.912
Swoo_0787
TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: sse:Ssed_3797 uroporphyrin-III C-methyltransferase; Belongs to the precorrin methyltransferase family.
     
 0.903
Swoo_1872
TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: sse:Ssed_2768 uroporphyrin-III C-methyltransferase.
     
 0.903
Swoo_1762
TIGRFAM: siroheme synthase; KEGG: sse:Ssed_2886 precorrin-2 oxidase / ferrochelatase.
     
  0.900
hemC
Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family.
  
  
 0.771
Swoo_0484
PFAM: adenylate cyclase class-I; KEGG: sse:Ssed_4132 adenylate cyclase; Belongs to the adenylyl cyclase class-1 family.
 
     0.669
lapB
Tetratricopeptide domain protein; Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane; Belongs to the LapB family.
  
     0.581
Swoo_3677
PFAM: Invasion gene expression up-regulator SirB; KEGG: sse:Ssed_3453 invasion gene expression up-regulator, SirB.
  
     0.571
Your Current Organism:
Shewanella woodyi
NCBI taxonomy Id: 392500
Other names: S. woodyi ATCC 51908, Shewanella woodyi ATCC 51908, Shewanella woodyi str. ATCC 51908, Shewanella woodyi strain ATCC 51908
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