STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cysISulfite reductase (NADPH) hemoprotein, beta-component; Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. Belongs to the nitrite and sulfite reductase 4Fe-4S domain family. (594 aa)    
Predicted Functional Partners:
Swoo_0776
Sulfite reductase (NADPH) flavoprotein, alpha chain; Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH -> FAD -> FMN to the hemoprotein component.
 
 0.999
cysH
Phosphoadenosine phosphosulfate reductase; Reduction of activated sulfate into sulfite. Belongs to the PAPS reductase family. CysH subfamily.
 
 
 0.999
Swoo_3288
PFAM: flavodoxin/nitric oxide synthase; KEGG: sse:Ssed_3168 flavodoxin/nitric oxide synthase.
 
 
 0.981
cysC
Adenylyl-sulfate kinase; Catalyzes the synthesis of activated sulfate.
 
  
 0.973
cysD
TIGRFAM: sulfate adenylyltransferase, small subunit; PFAM: phosphoadenosine phosphosulfate reductase; KEGG: sse:Ssed_2961 sulfate adenylyltransferase, small subunit.
  
  
 0.972
cysN
Sulfate adenylyltransferase, large subunit; May be the GTPase, regulating ATP sulfurylase activity. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.
  
  
 0.972
Swoo_2550
PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: sse:Ssed_2050 pyridoxal-5'-phosphate-dependent enzyme, beta subunit.
  
 
 0.962
Swoo_2857
TIGRFAM: cysteine synthase; cysteine synthase A; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: sse:Ssed_1721 cysteine synthase A; Belongs to the cysteine synthase/cystathionine beta- synthase family.
  
 
 0.962
glpE
Rhodanese domain protein; Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide.
    
 0.929
Swoo_0622
O-succinylhomoserine (thiol)-lyase; KEGG: sse:Ssed_4041 cystathionine gamma-synthase; TIGRFAM: O-succinylhomoserine (thiol)-lyase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein.
  
 
 0.929
Your Current Organism:
Shewanella woodyi
NCBI taxonomy Id: 392500
Other names: S. woodyi ATCC 51908, Shewanella woodyi ATCC 51908, Shewanella woodyi str. ATCC 51908, Shewanella woodyi strain ATCC 51908
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.