STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Swoo_0938PFAM: pentapeptide repeat protein; Ion transport 2 domain protein; KEGG: sse:Ssed_0839 ion transport 2 domain protein. (327 aa)    
Predicted Functional Partners:
Swoo_0028
KEGG: hch:HCH_00711 hypothetical protein.
  
     0.583
Swoo_0767
Transcriptional regulator, MerR family; PFAM: regulatory protein MerR; Methyltransferase type 11; Methyltransferase type 12; KEGG: sse:Ssed_1437 putative transcriptional regulator, MerR family.
 
   
 0.553
Swoo_2339
PFAM: GAD-like domain protein; Domain of unknown function DUF1851; KEGG: psp:PSPPH_0317 hypothetical protein.
  
     0.506
prfB
Hypothetical protein; Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.
       0.476
gyrB
DNA gyrase, B subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
   
 
 0.433
parE
DNA topoisomerase IV, B subunit; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase family. ParE type 1 subfamily.
   
 
 0.433
Swoo_2513
TIGRFAM: type VI secretion system Vgr family protein; PFAM: Rhs element Vgr protein; KEGG: eca:ECA3427 hypothetical protein.
  
    0.429
Swoo_2650
PFAM: Ion transport 2 domain protein; KEGG: prw:PsycPRwf_2088 ion transport 2 domain protein.
  
     0.424
Swoo_0937
TIGRFAM: formate dehydrogenase, alpha subunit; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; 4Fe-4S ferredoxin iron-sulfur binding domain protein; molybdopterin oxidoreductase; molydopterin dinucleotide-binding region; molybdopterin oxidoreductase Fe4S4 region; KEGG: sse:Ssed_0838 formate dehydrogenase, alpha subunit; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
       0.412
Swoo_4404
KEGG: sse:Ssed_0556 MSHA biogenesis protein MshP.
  
     0.402
Your Current Organism:
Shewanella woodyi
NCBI taxonomy Id: 392500
Other names: S. woodyi ATCC 51908, Shewanella woodyi ATCC 51908, Shewanella woodyi str. ATCC 51908, Shewanella woodyi strain ATCC 51908
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