STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mdhMalate dehydrogenase, NAD-dependent; Catalyzes the reversible oxidation of malate to oxaloacetate. (311 aa)    
Predicted Functional Partners:
Swoo_2227
Hydro-lyase, Fe-S type, tartrate/fumarate subfamily, alpha subunit; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.
  
 
 0.994
Swoo_1832
KEGG: sse:Ssed_2819 citrate (Si)-synthase; TIGRFAM: citrate synthase I; PFAM: Citrate synthase; Belongs to the citrate synthase family.
  
 0.981
fumC
Fumarate lyase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
  
 0.970
Swoo_1740
Conserved carboxylase region; PFAM: biotin/lipoyl attachment domain-containing protein; pyruvate carboxyltransferase; Conserved carboxylase region; KEGG: pat:Patl_3012 oxaloacetate decarboxylase alpha subunit.
    
 0.948
Swoo_3336
KEGG: sse:Ssed_1321 oxaloacetate decarboxylase; TIGRFAM: oxaloacetate decarboxylase alpha subunit; PFAM: biotin/lipoyl attachment domain-containing protein; pyruvate carboxyltransferase; Conserved carboxylase region.
    
 0.948
maeA
Malate dehydrogenase (oxaloacetate-decarboxylating); PFAM: malic protein domain protein; malic protein NAD-binding; KEGG: sse:Ssed_3518 malate dehydrogenase (oxaloacetate-decarboxylating); Belongs to the malic enzymes family.
  
 0.935
Swoo_4423
PFAM: malic protein domain protein; malic protein NAD-binding; KEGG: slo:Shew_0383 malate dehydrogenase (oxaloacetate-decarboxylating) (NADP(+)).
  
 0.935
pckA
Phosphoenolpyruvate carboxykinase (ATP); Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA. Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.
  
 
 0.935
ppc
Phosphoenolpyruvate carboxylase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle; Belongs to the PEPCase type 1 family.
     
 0.932
Swoo_2308
Aspartate transaminase; PFAM: aminotransferase class I and II; KEGG: sse:Ssed_2301 aspartate transaminase.
   
 0.931
Your Current Organism:
Shewanella woodyi
NCBI taxonomy Id: 392500
Other names: S. woodyi ATCC 51908, Shewanella woodyi ATCC 51908, Shewanella woodyi str. ATCC 51908, Shewanella woodyi strain ATCC 51908
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.