Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Swoo_1328KEGG: sse:Ssed_1228 hypothetical protein. (144 aa)    
Predicted Functional Partners:
Swoo_1327
Non-canonical purine NTP pyrophosphatase, rdgB/HAM1 family; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.
  
    0.842
Swoo_2163
KEGG: sse:Ssed_2442 hypothetical protein.
  
     0.725
Swoo_1330
PFAM: protein of unknown function YGGT; KEGG: sse:Ssed_1230 protein of unknown function YGGT.
       0.698
Swoo_1329
PFAM: protein of unknown function DUF167; KEGG: sse:Ssed_1229 protein of unknown function DUF167; Belongs to the UPF0235 family.
       0.680
Swoo_1079
PFAM: RDD domain containing protein; KEGG: sse:Ssed_1017 RDD domain containing protein.
  
     0.656
proC
Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
       0.608
Swoo_2144
PFAM: glutaredoxin 2; KEGG: spl:Spea_1947 glutaredoxin 2.
  
     0.579
Swoo_2421
KEGG: sse:Ssed_2215 hypothetical protein.
  
     0.553
Swoo_1326
Oxygen-independent coproporphyrinogen III oxidase; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family.
       0.535
Swoo_4725
General secretion pathway M protein; Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins.
  
     0.516
Your Current Organism:
Shewanella woodyi
NCBI taxonomy Id: 392500
Other names: S. woodyi ATCC 51908, Shewanella woodyi ATCC 51908, Shewanella woodyi str. ATCC 51908, Shewanella woodyi strain ATCC 51908
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