| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Swoo_1326 | Swoo_1327 | Swoo_1326 | Swoo_1327 | Oxygen-independent coproporphyrinogen III oxidase; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family. | Non-canonical purine NTP pyrophosphatase, rdgB/HAM1 family; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | 0.809 |
| Swoo_1326 | Swoo_1329 | Swoo_1326 | Swoo_1329 | Oxygen-independent coproporphyrinogen III oxidase; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family. | PFAM: protein of unknown function DUF167; KEGG: sse:Ssed_1229 protein of unknown function DUF167; Belongs to the UPF0235 family. | 0.543 |
| Swoo_1326 | Swoo_1330 | Swoo_1326 | Swoo_1330 | Oxygen-independent coproporphyrinogen III oxidase; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family. | PFAM: protein of unknown function YGGT; KEGG: sse:Ssed_1230 protein of unknown function YGGT. | 0.486 |
| Swoo_1326 | Swoo_1332 | Swoo_1326 | Swoo_1332 | Oxygen-independent coproporphyrinogen III oxidase; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family. | Alanine racemase domain protein; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family. | 0.655 |
| Swoo_1326 | Swoo_4399 | Swoo_1326 | Swoo_4399 | Oxygen-independent coproporphyrinogen III oxidase; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family. | Maf protein; Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. | 0.478 |
| Swoo_1326 | proC | Swoo_1326 | Swoo_1331 | Oxygen-independent coproporphyrinogen III oxidase; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family. | Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. | 0.545 |
| Swoo_1327 | Swoo_1326 | Swoo_1327 | Swoo_1326 | Non-canonical purine NTP pyrophosphatase, rdgB/HAM1 family; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | Oxygen-independent coproporphyrinogen III oxidase; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family. | 0.809 |
| Swoo_1327 | Swoo_1329 | Swoo_1327 | Swoo_1329 | Non-canonical purine NTP pyrophosphatase, rdgB/HAM1 family; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | PFAM: protein of unknown function DUF167; KEGG: sse:Ssed_1229 protein of unknown function DUF167; Belongs to the UPF0235 family. | 0.527 |
| Swoo_1327 | Swoo_1330 | Swoo_1327 | Swoo_1330 | Non-canonical purine NTP pyrophosphatase, rdgB/HAM1 family; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | PFAM: protein of unknown function YGGT; KEGG: sse:Ssed_1230 protein of unknown function YGGT. | 0.590 |
| Swoo_1327 | Swoo_1332 | Swoo_1327 | Swoo_1332 | Non-canonical purine NTP pyrophosphatase, rdgB/HAM1 family; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | Alanine racemase domain protein; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family. | 0.606 |
| Swoo_1327 | Swoo_1333 | Swoo_1327 | Swoo_1333 | Non-canonical purine NTP pyrophosphatase, rdgB/HAM1 family; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | KEGG: sse:Ssed_1233 twitching motility protein PilT; TIGRFAM: twitching motility protein; PFAM: type II secretion system protein E; SMART: AAA ATPase. | 0.433 |
| Swoo_1327 | proC | Swoo_1327 | Swoo_1331 | Non-canonical purine NTP pyrophosphatase, rdgB/HAM1 family; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. | 0.601 |
| Swoo_1329 | Swoo_1326 | Swoo_1329 | Swoo_1326 | PFAM: protein of unknown function DUF167; KEGG: sse:Ssed_1229 protein of unknown function DUF167; Belongs to the UPF0235 family. | Oxygen-independent coproporphyrinogen III oxidase; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family. | 0.543 |
| Swoo_1329 | Swoo_1327 | Swoo_1329 | Swoo_1327 | PFAM: protein of unknown function DUF167; KEGG: sse:Ssed_1229 protein of unknown function DUF167; Belongs to the UPF0235 family. | Non-canonical purine NTP pyrophosphatase, rdgB/HAM1 family; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | 0.527 |
| Swoo_1329 | Swoo_1330 | Swoo_1329 | Swoo_1330 | PFAM: protein of unknown function DUF167; KEGG: sse:Ssed_1229 protein of unknown function DUF167; Belongs to the UPF0235 family. | PFAM: protein of unknown function YGGT; KEGG: sse:Ssed_1230 protein of unknown function YGGT. | 0.867 |
| Swoo_1329 | Swoo_1332 | Swoo_1329 | Swoo_1332 | PFAM: protein of unknown function DUF167; KEGG: sse:Ssed_1229 protein of unknown function DUF167; Belongs to the UPF0235 family. | Alanine racemase domain protein; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family. | 0.685 |
| Swoo_1329 | Swoo_1333 | Swoo_1329 | Swoo_1333 | PFAM: protein of unknown function DUF167; KEGG: sse:Ssed_1229 protein of unknown function DUF167; Belongs to the UPF0235 family. | KEGG: sse:Ssed_1233 twitching motility protein PilT; TIGRFAM: twitching motility protein; PFAM: type II secretion system protein E; SMART: AAA ATPase. | 0.468 |
| Swoo_1329 | Swoo_1334 | Swoo_1329 | Swoo_1334 | PFAM: protein of unknown function DUF167; KEGG: sse:Ssed_1229 protein of unknown function DUF167; Belongs to the UPF0235 family. | TIGRFAM: twitching motility protein; PFAM: type II secretion system protein E; KEGG: sse:Ssed_1234 twitching motility protein. | 0.448 |
| Swoo_1329 | proC | Swoo_1329 | Swoo_1331 | PFAM: protein of unknown function DUF167; KEGG: sse:Ssed_1229 protein of unknown function DUF167; Belongs to the UPF0235 family. | Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. | 0.700 |
| Swoo_1330 | Swoo_1326 | Swoo_1330 | Swoo_1326 | PFAM: protein of unknown function YGGT; KEGG: sse:Ssed_1230 protein of unknown function YGGT. | Oxygen-independent coproporphyrinogen III oxidase; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family. | 0.486 |