| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Swoo_0002 | Swoo_1337 | Swoo_0002 | Swoo_1337 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | PFAM: protein of unknown function DUF179; KEGG: sse:Ssed_1237 protein of unknown function DUF179; Belongs to the UPF0301 (AlgH) family. | 0.709 |
| Swoo_0002 | Swoo_2303 | Swoo_0002 | Swoo_2303 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | Ribonucleoside-diphosphate reductase, alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | 0.778 |
| Swoo_0002 | thyA | Swoo_0002 | Swoo_1230 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. | 0.762 |
| Swoo_1336 | Swoo_1337 | Swoo_1336 | Swoo_1337 | Holliday junction resolvase YqgF; Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA; Belongs to the YqgF HJR family. | PFAM: protein of unknown function DUF179; KEGG: sse:Ssed_1237 protein of unknown function DUF179; Belongs to the UPF0301 (AlgH) family. | 0.931 |
| Swoo_1336 | Swoo_1338 | Swoo_1336 | Swoo_1338 | Holliday junction resolvase YqgF; Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA; Belongs to the YqgF HJR family. | PFAM: translation initiation factor SUI1; KEGG: spl:Spea_1133 translation initiation factor SUI1. | 0.499 |
| Swoo_1337 | Swoo_0002 | Swoo_1337 | Swoo_0002 | PFAM: protein of unknown function DUF179; KEGG: sse:Ssed_1237 protein of unknown function DUF179; Belongs to the UPF0301 (AlgH) family. | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.709 |
| Swoo_1337 | Swoo_1336 | Swoo_1337 | Swoo_1336 | PFAM: protein of unknown function DUF179; KEGG: sse:Ssed_1237 protein of unknown function DUF179; Belongs to the UPF0301 (AlgH) family. | Holliday junction resolvase YqgF; Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA; Belongs to the YqgF HJR family. | 0.931 |
| Swoo_1337 | Swoo_1338 | Swoo_1337 | Swoo_1338 | PFAM: protein of unknown function DUF179; KEGG: sse:Ssed_1237 protein of unknown function DUF179; Belongs to the UPF0301 (AlgH) family. | PFAM: translation initiation factor SUI1; KEGG: spl:Spea_1133 translation initiation factor SUI1. | 0.650 |
| Swoo_1337 | Swoo_1834 | Swoo_1337 | Swoo_1834 | PFAM: protein of unknown function DUF179; KEGG: sse:Ssed_1237 protein of unknown function DUF179; Belongs to the UPF0301 (AlgH) family. | Succinate dehydrogenase, hydrophobic membrane anchor protein; Membrane-anchoring subunit of succinate dehydrogenase (SDH). | 0.483 |
| Swoo_1337 | Swoo_2303 | Swoo_1337 | Swoo_2303 | PFAM: protein of unknown function DUF179; KEGG: sse:Ssed_1237 protein of unknown function DUF179; Belongs to the UPF0301 (AlgH) family. | Ribonucleoside-diphosphate reductase, alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | 0.947 |
| Swoo_1337 | Swoo_4505 | Swoo_1337 | Swoo_4505 | PFAM: protein of unknown function DUF179; KEGG: sse:Ssed_1237 protein of unknown function DUF179; Belongs to the UPF0301 (AlgH) family. | PFAM: band 7 protein; KEGG: sse:Ssed_0465 band 7 protein. | 0.475 |
| Swoo_1337 | Swoo_4863 | Swoo_1337 | Swoo_4863 | PFAM: protein of unknown function DUF179; KEGG: sse:Ssed_1237 protein of unknown function DUF179; Belongs to the UPF0301 (AlgH) family. | PFAM: regulatory protein GntR HTH; KEGG: spl:Spea_4189 transcriptional regulator, GntR family. | 0.521 |
| Swoo_1337 | nuoC | Swoo_1337 | Swoo_2862 | PFAM: protein of unknown function DUF179; KEGG: sse:Ssed_1237 protein of unknown function DUF179; Belongs to the UPF0301 (AlgH) family. | NADH dehydrogenase I, D subunit; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; In the N-terminal section; belongs to the complex I 30 kDa subunit family. | 0.481 |
| Swoo_1337 | tdk | Swoo_1337 | Swoo_3233 | PFAM: protein of unknown function DUF179; KEGG: sse:Ssed_1237 protein of unknown function DUF179; Belongs to the UPF0301 (AlgH) family. | PFAM: thymidine kinase; KEGG: spl:Spea_2851 thymidine kinase. | 0.530 |
| Swoo_1337 | thyA | Swoo_1337 | Swoo_1230 | PFAM: protein of unknown function DUF179; KEGG: sse:Ssed_1237 protein of unknown function DUF179; Belongs to the UPF0301 (AlgH) family. | Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. | 0.522 |
| Swoo_1338 | Swoo_1336 | Swoo_1338 | Swoo_1336 | PFAM: translation initiation factor SUI1; KEGG: spl:Spea_1133 translation initiation factor SUI1. | Holliday junction resolvase YqgF; Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA; Belongs to the YqgF HJR family. | 0.499 |
| Swoo_1338 | Swoo_1337 | Swoo_1338 | Swoo_1337 | PFAM: translation initiation factor SUI1; KEGG: spl:Spea_1133 translation initiation factor SUI1. | PFAM: protein of unknown function DUF179; KEGG: sse:Ssed_1237 protein of unknown function DUF179; Belongs to the UPF0301 (AlgH) family. | 0.650 |
| Swoo_1834 | Swoo_1337 | Swoo_1834 | Swoo_1337 | Succinate dehydrogenase, hydrophobic membrane anchor protein; Membrane-anchoring subunit of succinate dehydrogenase (SDH). | PFAM: protein of unknown function DUF179; KEGG: sse:Ssed_1237 protein of unknown function DUF179; Belongs to the UPF0301 (AlgH) family. | 0.483 |
| Swoo_1834 | nuoC | Swoo_1834 | Swoo_2862 | Succinate dehydrogenase, hydrophobic membrane anchor protein; Membrane-anchoring subunit of succinate dehydrogenase (SDH). | NADH dehydrogenase I, D subunit; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; In the N-terminal section; belongs to the complex I 30 kDa subunit family. | 0.909 |
| Swoo_2303 | Swoo_0002 | Swoo_2303 | Swoo_0002 | Ribonucleoside-diphosphate reductase, alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.778 |