Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
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[Homology]
Score
Swoo_1407Aminocarboxymuconate-semialdehyde decarboxylase; PFAM: amidohydrolase 2; KEGG: aba:Acid345_0682 tryptophan 2,3-dioxygenase. (339 aa)    
Predicted Functional Partners:
nbaC
3-hydroxyanthranilate 3,4-dioxygenase; Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate.
 
  
  0.995
Swoo_1410
TIGRFAM: 2-hydroxymuconic semialdehyde dehydrogenase; PFAM: Aldehyde Dehydrogenase; KEGG: pol:Bpro_5132 aldehyde dehydrogenase.
 
  
 0.961
kynU
Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively.
 
  
 0.912
kmo
Kynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid; Belongs to the aromatic-ring hydroxylase family. KMO subfamily.
 
  
 0.900
Swoo_1409
PFAM: Endoribonuclease L-PSP; KEGG: reu:Reut_B5501 endoribonuclease L-PSP.
 
    0.851
Swoo_1406
PFAM: Hydratase/decarboxylase; KEGG: swi:Swit_0912 4-oxalocrotonate decarboxylase.
 
   
 0.797
kynA
Tryptophan 23-dioxygenase; Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety.
 
  
 0.681
Swoo_1402
KEGG: bbr:BB4423 putative esterase.
 
   
 0.673
Swoo_1987
PFAM: nucleoside recognition domain protein; KEGG: sse:Ssed_2643 nucleoside recognition domain protein.
   
    0.487
Swoo_2919
Arachidonate 15-lipoxygenase; PFAM: Lipoxygenase; KEGG: amr:AM1_3903 lipoxygenase.
  
     0.423
Your Current Organism:
Shewanella woodyi
NCBI taxonomy Id: 392500
Other names: S. woodyi ATCC 51908, Shewanella woodyi ATCC 51908, Shewanella woodyi str. ATCC 51908, Shewanella woodyi strain ATCC 51908
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