| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Swoo_1382 | carB | Swoo_1382 | Swoo_3577 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | TIGRFAM: carbamoyl-phosphate synthase, large subunit; PFAM: ATP-dependent carboxylate-amine ligase domain protein ATP-grasp; protein of unknown function DUF201; Carbamoyl-phosphate synthase L chain ATP-binding; Carbamoyl-phosphate synthetase large chain oligomerisation; Carbamoyl-phosphate synthetase large chain domain protein; MGS domain protein; KEGG: sse:Ssed_3403 carbamoyl-phosphate synthase, large subunit; Belongs to the CarB family. | 0.702 |
| Swoo_1382 | guaA | Swoo_1382 | Swoo_1560 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP. | 0.692 |
| Swoo_1382 | pdxA | Swoo_1382 | Swoo_1015 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 4-hydroxythreonine-4-phosphate dehydrogenase; Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L- threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP). | 0.592 |
| Swoo_1382 | pdxH | Swoo_1382 | Swoo_2060 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | Pyridoxamine 5'-phosphate oxidase; Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP). | 0.577 |
| Swoo_1382 | pdxJ | Swoo_1382 | Swoo_1246 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | Pyridoxal phosphate biosynthetic protein PdxJ; Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino- 2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate. | 0.643 |
| Swoo_2058 | Swoo_2059 | Swoo_2058 | Swoo_2059 | PFAM: S-adenosylmethionine decarboxylase; KEGG: sse:Ssed_2608 adenosylmethionine decarboxylase. | TIGRFAM: agmatinase; PFAM: Arginase/agmatinase/formiminoglutamase; KEGG: slo:Shew_1621 putative agmatinase; Belongs to the arginase family. | 0.708 |
| Swoo_2058 | pdxH | Swoo_2058 | Swoo_2060 | PFAM: S-adenosylmethionine decarboxylase; KEGG: sse:Ssed_2608 adenosylmethionine decarboxylase. | Pyridoxamine 5'-phosphate oxidase; Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP). | 0.580 |
| Swoo_2058 | speA | Swoo_2058 | Swoo_2057 | PFAM: S-adenosylmethionine decarboxylase; KEGG: sse:Ssed_2608 adenosylmethionine decarboxylase. | Arginine decarboxylase; Catalyzes the biosynthesis of agmatine from arginine. | 0.599 |
| Swoo_2059 | Swoo_2058 | Swoo_2059 | Swoo_2058 | TIGRFAM: agmatinase; PFAM: Arginase/agmatinase/formiminoglutamase; KEGG: slo:Shew_1621 putative agmatinase; Belongs to the arginase family. | PFAM: S-adenosylmethionine decarboxylase; KEGG: sse:Ssed_2608 adenosylmethionine decarboxylase. | 0.708 |
| Swoo_2059 | pdxH | Swoo_2059 | Swoo_2060 | TIGRFAM: agmatinase; PFAM: Arginase/agmatinase/formiminoglutamase; KEGG: slo:Shew_1621 putative agmatinase; Belongs to the arginase family. | Pyridoxamine 5'-phosphate oxidase; Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP). | 0.709 |
| Swoo_2059 | speA | Swoo_2059 | Swoo_2057 | TIGRFAM: agmatinase; PFAM: Arginase/agmatinase/formiminoglutamase; KEGG: slo:Shew_1621 putative agmatinase; Belongs to the arginase family. | Arginine decarboxylase; Catalyzes the biosynthesis of agmatine from arginine. | 0.980 |
| carB | Swoo_1382 | Swoo_3577 | Swoo_1382 | TIGRFAM: carbamoyl-phosphate synthase, large subunit; PFAM: ATP-dependent carboxylate-amine ligase domain protein ATP-grasp; protein of unknown function DUF201; Carbamoyl-phosphate synthase L chain ATP-binding; Carbamoyl-phosphate synthetase large chain oligomerisation; Carbamoyl-phosphate synthetase large chain domain protein; MGS domain protein; KEGG: sse:Ssed_3403 carbamoyl-phosphate synthase, large subunit; Belongs to the CarB family. | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.702 |
| carB | guaA | Swoo_3577 | Swoo_1560 | TIGRFAM: carbamoyl-phosphate synthase, large subunit; PFAM: ATP-dependent carboxylate-amine ligase domain protein ATP-grasp; protein of unknown function DUF201; Carbamoyl-phosphate synthase L chain ATP-binding; Carbamoyl-phosphate synthetase large chain oligomerisation; Carbamoyl-phosphate synthetase large chain domain protein; MGS domain protein; KEGG: sse:Ssed_3403 carbamoyl-phosphate synthase, large subunit; Belongs to the CarB family. | GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP. | 0.895 |
| carB | pdxH | Swoo_3577 | Swoo_2060 | TIGRFAM: carbamoyl-phosphate synthase, large subunit; PFAM: ATP-dependent carboxylate-amine ligase domain protein ATP-grasp; protein of unknown function DUF201; Carbamoyl-phosphate synthase L chain ATP-binding; Carbamoyl-phosphate synthetase large chain oligomerisation; Carbamoyl-phosphate synthetase large chain domain protein; MGS domain protein; KEGG: sse:Ssed_3403 carbamoyl-phosphate synthase, large subunit; Belongs to the CarB family. | Pyridoxamine 5'-phosphate oxidase; Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP). | 0.512 |
| gcvP | guaA | Swoo_3967 | Swoo_1560 | Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP. | 0.650 |
| gcvP | pdxH | Swoo_3967 | Swoo_2060 | Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | Pyridoxamine 5'-phosphate oxidase; Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP). | 0.502 |
| guaA | Swoo_1382 | Swoo_1560 | Swoo_1382 | GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP. | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.692 |
| guaA | carB | Swoo_1560 | Swoo_3577 | GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP. | TIGRFAM: carbamoyl-phosphate synthase, large subunit; PFAM: ATP-dependent carboxylate-amine ligase domain protein ATP-grasp; protein of unknown function DUF201; Carbamoyl-phosphate synthase L chain ATP-binding; Carbamoyl-phosphate synthetase large chain oligomerisation; Carbamoyl-phosphate synthetase large chain domain protein; MGS domain protein; KEGG: sse:Ssed_3403 carbamoyl-phosphate synthase, large subunit; Belongs to the CarB family. | 0.895 |
| guaA | gcvP | Swoo_1560 | Swoo_3967 | GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP. | Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.650 |
| guaA | pdxH | Swoo_1560 | Swoo_2060 | GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP. | Pyridoxamine 5'-phosphate oxidase; Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP). | 0.565 |