Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Swoo_2131KEGG: sfr:Sfri_2230 putative GAF sensor protein. (152 aa)    
Predicted Functional Partners:
Swoo_2411
Aspartate transaminase; PFAM: aminotransferase class I and II; KEGG: sse:Ssed_2225 aspartate transaminase.
 
  
  0.919
Swoo_3095
Methionine gamma-lyase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein; aromatic amino acid beta-eliminating lyase/threonine aldolase; KEGG: sse:Ssed_1559 methionine gamma-lyase.
     
 0.902
Swoo_3427
O-acetylhomoserine/O-acetylserine sulfhydrylase; KEGG: sse:Ssed_3283 O-acetylhomoserine aminocarboxypropyltransferase; TIGRFAM: O-acetylhomoserine/O-acetylserine sulfhydrylase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein; aromatic amino acid beta-eliminating lyase/threonine aldolase.
    
  0.902
Swoo_0588
dTDP-4-dehydrorhamnose reductase; Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose; Belongs to the dTDP-4-dehydrorhamnose reductase family.
     
  0.900
metK
Methionine adenosyltransferase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
     
  0.900
Swoo_4088
Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
     
  0.900
Swoo_4458
PFAM: Methionine synthase vitamin-B12 independent; KEGG: cps:CPS_1151 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase.
     
  0.900
Swoo_2130
PFAM: YebG family protein; KEGG: sse:Ssed_2486 YebG family protein.
  
    0.775
proQ
ProQ activator of osmoprotectant transporter ProP; RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities; Belongs to the ProQ family.
  
  
 0.711
Swoo_2133
Carboxyl-terminal protease; KEGG: sse:Ssed_2483 C-terminal processing peptidase; TIGRFAM: carboxyl-terminal protease; PFAM: PDZ/DHR/GLGF domain protein; peptidase S41; Belongs to the peptidase S41A family.
     
 0.595
Your Current Organism:
Shewanella woodyi
NCBI taxonomy Id: 392500
Other names: S. woodyi ATCC 51908, Shewanella woodyi ATCC 51908, Shewanella woodyi str. ATCC 51908, Shewanella woodyi strain ATCC 51908
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