| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Swoo_0621 | Swoo_2786 | Swoo_0621 | Swoo_2786 | Methionine repressor, MetJ; This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis. | PFAM: protein of unknown function DUF1414; KEGG: sse:Ssed_1809 protein of unknown function DUF1414; Belongs to the UPF0352 family. | 0.734 |
| Swoo_0621 | Swoo_2885 | Swoo_0621 | Swoo_2885 | Methionine repressor, MetJ; This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis. | PFAM: protein of unknown function DUF412; KEGG: sse:Ssed_1706 protein of unknown function DUF412. | 0.752 |
| Swoo_0621 | Swoo_3356 | Swoo_0621 | Swoo_3356 | Methionine repressor, MetJ; This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis. | PFAM: protein of unknown function DUF416; KEGG: sse:Ssed_1284 protein of unknown function DUF416. | 0.443 |
| Swoo_0621 | Swoo_3555 | Swoo_0621 | Swoo_3555 | Methionine repressor, MetJ; This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis. | TPR repeat-containing protein; May be involved in cell division. | 0.764 |
| Swoo_0621 | bamC | Swoo_0621 | Swoo_2178 | Methionine repressor, MetJ; This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis. | NlpBDapX family lipoprotein; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. | 0.613 |
| Swoo_0621 | dsbB | Swoo_0621 | Swoo_2691 | Methionine repressor, MetJ; This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis. | Disulphide bond formation protein DsbB; Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein; Belongs to the DsbB family. | 0.698 |
| Swoo_0621 | proQ | Swoo_0621 | Swoo_2132 | Methionine repressor, MetJ; This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis. | ProQ activator of osmoprotectant transporter ProP; RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities; Belongs to the ProQ family. | 0.745 |
| Swoo_0621 | rraB | Swoo_0621 | Swoo_4330 | Methionine repressor, MetJ; This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis. | Protein of unknown function DUF1260; Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. | 0.773 |
| Swoo_0621 | seqA | Swoo_0621 | Swoo_2274 | Methionine repressor, MetJ; This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis. | SeqA family protein; Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated. | 0.820 |
| Swoo_2133 | Swoo_3555 | Swoo_2133 | Swoo_3555 | Carboxyl-terminal protease; KEGG: sse:Ssed_2483 C-terminal processing peptidase; TIGRFAM: carboxyl-terminal protease; PFAM: PDZ/DHR/GLGF domain protein; peptidase S41; Belongs to the peptidase S41A family. | TPR repeat-containing protein; May be involved in cell division. | 0.787 |
| Swoo_2133 | proQ | Swoo_2133 | Swoo_2132 | Carboxyl-terminal protease; KEGG: sse:Ssed_2483 C-terminal processing peptidase; TIGRFAM: carboxyl-terminal protease; PFAM: PDZ/DHR/GLGF domain protein; peptidase S41; Belongs to the peptidase S41A family. | ProQ activator of osmoprotectant transporter ProP; RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities; Belongs to the ProQ family. | 0.787 |
| Swoo_2786 | Swoo_0621 | Swoo_2786 | Swoo_0621 | PFAM: protein of unknown function DUF1414; KEGG: sse:Ssed_1809 protein of unknown function DUF1414; Belongs to the UPF0352 family. | Methionine repressor, MetJ; This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis. | 0.734 |
| Swoo_2786 | Swoo_2885 | Swoo_2786 | Swoo_2885 | PFAM: protein of unknown function DUF1414; KEGG: sse:Ssed_1809 protein of unknown function DUF1414; Belongs to the UPF0352 family. | PFAM: protein of unknown function DUF412; KEGG: sse:Ssed_1706 protein of unknown function DUF412. | 0.742 |
| Swoo_2786 | Swoo_3555 | Swoo_2786 | Swoo_3555 | PFAM: protein of unknown function DUF1414; KEGG: sse:Ssed_1809 protein of unknown function DUF1414; Belongs to the UPF0352 family. | TPR repeat-containing protein; May be involved in cell division. | 0.746 |
| Swoo_2786 | bamC | Swoo_2786 | Swoo_2178 | PFAM: protein of unknown function DUF1414; KEGG: sse:Ssed_1809 protein of unknown function DUF1414; Belongs to the UPF0352 family. | NlpBDapX family lipoprotein; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. | 0.674 |
| Swoo_2786 | dsbB | Swoo_2786 | Swoo_2691 | PFAM: protein of unknown function DUF1414; KEGG: sse:Ssed_1809 protein of unknown function DUF1414; Belongs to the UPF0352 family. | Disulphide bond formation protein DsbB; Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein; Belongs to the DsbB family. | 0.611 |
| Swoo_2786 | proQ | Swoo_2786 | Swoo_2132 | PFAM: protein of unknown function DUF1414; KEGG: sse:Ssed_1809 protein of unknown function DUF1414; Belongs to the UPF0352 family. | ProQ activator of osmoprotectant transporter ProP; RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities; Belongs to the ProQ family. | 0.726 |
| Swoo_2786 | rraB | Swoo_2786 | Swoo_4330 | PFAM: protein of unknown function DUF1414; KEGG: sse:Ssed_1809 protein of unknown function DUF1414; Belongs to the UPF0352 family. | Protein of unknown function DUF1260; Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. | 0.767 |
| Swoo_2786 | seqA | Swoo_2786 | Swoo_2274 | PFAM: protein of unknown function DUF1414; KEGG: sse:Ssed_1809 protein of unknown function DUF1414; Belongs to the UPF0352 family. | SeqA family protein; Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated. | 0.774 |
| Swoo_2885 | Swoo_0621 | Swoo_2885 | Swoo_0621 | PFAM: protein of unknown function DUF412; KEGG: sse:Ssed_1706 protein of unknown function DUF412. | Methionine repressor, MetJ; This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis. | 0.752 |