Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Swoo_2169Peptidase M48 Ste24p; Functions as both a chaperone and a metalloprotease. Maintains the integrity of the outer membrane by promoting either the assembly or the elimination of outer membrane proteins, depending on their folding state. (486 aa)    
Predicted Functional Partners:
Swoo_4485
Transcriptional regulator, CadC; PFAM: TPR repeat-containing protein; transcriptional regulator domain protein; Tetratricopeptide TPR_2 repeat protein; SMART: Tetratricopeptide domain protein; KEGG: sdn:Sden_3304 transcriptional regulatory protein-like protein.
   
 
 0.720
Swoo_2168
TIGRFAM: arsenate reductase; PFAM: arsenate reductase and related; KEGG: sse:Ssed_2438 arsenate reductase.
  
  
 0.646
Swoo_0567
PFAM: peptidase M48 Ste24p; KEGG: vvy:VV2911 Zn-dependent protease with chaperone function.
  
     0.565
lptD
Organic solvent tolerance protein; Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane.
  
  
 0.553
Swoo_2167
KEGG: sse:Ssed_2439 hypothetical protein.
 
   
 0.550
Swoo_2171
PFAM: protein of unknown function UPF0118; KEGG: sse:Ssed_2435 protein of unknown function UPF0118.
       0.540
Swoo_2170
PFAM: SirA family protein; KEGG: sse:Ssed_2436 SirA family protein; Belongs to the sulfur carrier protein TusA family.
       0.483
Swoo_1264
TIGRFAM: ribosomal subunit interface protein; PFAM: sigma 54 modulation protein/ribosomal protein S30EA; KEGG: sse:Ssed_1169 ribosomal subunit interface protein.
  
     0.477
Swoo_0400
PFAM: DSBA oxidoreductase; KEGG: sse:Ssed_4193 DsbA oxidoreductase.
 
   
 0.452
surA
SurA domain; Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation.
 
  
 0.444
Your Current Organism:
Shewanella woodyi
NCBI taxonomy Id: 392500
Other names: S. woodyi ATCC 51908, Shewanella woodyi ATCC 51908, Shewanella woodyi str. ATCC 51908, Shewanella woodyi strain ATCC 51908
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