STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Swoo_2270Flavodoxin; Low-potential electron donor to a number of redox enzymes. Belongs to the flavodoxin family. (175 aa)    
Predicted Functional Partners:
Swoo_2271
PFAM: CopG domain protein DNA-binding domain protein; KEGG: sse:Ssed_2336 CopG domain protein DNA-binding domain protein.
  
  
 0.720
Swoo_2272
KEGG: spl:Spea_2053 conserved hypothetical protein.
 
     0.700
seqA
SeqA family protein; Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated.
 
  
 0.573
fur
Ferric uptake regulator, Fur family; PFAM: ferric-uptake regulator; KEGG: sse:Ssed_2810 ferric uptake regulator, Fur family; Belongs to the Fur family.
  
  
 0.518
Swoo_1137
PFAM: pyruvate ferredoxin/flavodoxin oxidoreductase; pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; KEGG: sse:Ssed_1068 2-ketoglutarate: NADP oxidoreductase, alpha subunit.
     
 0.515
Swoo_3555
TPR repeat-containing protein; May be involved in cell division.
  
     0.480
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
  
   
 0.460
Swoo_2302
PFAM: ribonucleotide reductase; KEGG: slo:Shew_1945 ribonucleoside-diphosphate reductase.
 
    0.459
rraB
Protein of unknown function DUF1260; Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome.
  
     0.449
Swoo_0978
PFAM: isochorismatase hydrolase; KEGG: sse:Ssed_0932 isochorismatase hydrolase.
   
    0.447
Your Current Organism:
Shewanella woodyi
NCBI taxonomy Id: 392500
Other names: S. woodyi ATCC 51908, Shewanella woodyi ATCC 51908, Shewanella woodyi str. ATCC 51908, Shewanella woodyi strain ATCC 51908
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.