node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Swoo_1374 | Swoo_2292 | Swoo_1374 | Swoo_2292 | PFAM: metallophosphoesterase; KEGG: sse:Ssed_1269 metallophosphoesterase. | ATP-dependent DNA helicase, RecQ family; KEGG: sse:Ssed_2318 23S rRNA (Gm2251)-methyltransferase; TIGRFAM: ATP-dependent DNA helicase, RecQ family; PFAM: helicase domain protein; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases. | 0.814 |
Swoo_1374 | Swoo_4552 | Swoo_1374 | Swoo_4552 | PFAM: metallophosphoesterase; KEGG: sse:Ssed_1269 metallophosphoesterase. | KEGG: sse:Ssed_0391 ATP-dependent DNA helicase RecQ; TIGRFAM: ATP-dependent DNA helicase, RecQ family; ATP-dependent DNA helicase RecQ; PFAM: helicase domain protein; HRDC domain protein; DEAD/DEAH box helicase domain protein; Helicase superfamily 1 and 2 ATP-binding; SMART: DEAD-like helicases. | 0.814 |
Swoo_1374 | polA | Swoo_1374 | Swoo_0060 | PFAM: metallophosphoesterase; KEGG: sse:Ssed_1269 metallophosphoesterase. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.954 |
Swoo_1374 | recA | Swoo_1374 | Swoo_3340 | PFAM: metallophosphoesterase; KEGG: sse:Ssed_1269 metallophosphoesterase. | recA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.678 |
Swoo_1374 | topA | Swoo_1374 | Swoo_1803 | PFAM: metallophosphoesterase; KEGG: sse:Ssed_1269 metallophosphoesterase. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.483 |
Swoo_1374 | topB | Swoo_1374 | Swoo_2976 | PFAM: metallophosphoesterase; KEGG: sse:Ssed_1269 metallophosphoesterase. | DNA topoisomerase III; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA su [...] | 0.448 |
Swoo_1374 | xni | Swoo_1374 | Swoo_3460 | PFAM: metallophosphoesterase; KEGG: sse:Ssed_1269 metallophosphoesterase. | 5'-3' exonuclease; Has flap endonuclease activity. During DNA replication, flap endonucleases cleave the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. | 0.795 |
Swoo_2292 | Swoo_1374 | Swoo_2292 | Swoo_1374 | ATP-dependent DNA helicase, RecQ family; KEGG: sse:Ssed_2318 23S rRNA (Gm2251)-methyltransferase; TIGRFAM: ATP-dependent DNA helicase, RecQ family; PFAM: helicase domain protein; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases. | PFAM: metallophosphoesterase; KEGG: sse:Ssed_1269 metallophosphoesterase. | 0.814 |
Swoo_2292 | Swoo_4552 | Swoo_2292 | Swoo_4552 | ATP-dependent DNA helicase, RecQ family; KEGG: sse:Ssed_2318 23S rRNA (Gm2251)-methyltransferase; TIGRFAM: ATP-dependent DNA helicase, RecQ family; PFAM: helicase domain protein; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases. | KEGG: sse:Ssed_0391 ATP-dependent DNA helicase RecQ; TIGRFAM: ATP-dependent DNA helicase, RecQ family; ATP-dependent DNA helicase RecQ; PFAM: helicase domain protein; HRDC domain protein; DEAD/DEAH box helicase domain protein; Helicase superfamily 1 and 2 ATP-binding; SMART: DEAD-like helicases. | 0.920 |
Swoo_2292 | deaD | Swoo_2292 | Swoo_0636 | ATP-dependent DNA helicase, RecQ family; KEGG: sse:Ssed_2318 23S rRNA (Gm2251)-methyltransferase; TIGRFAM: ATP-dependent DNA helicase, RecQ family; PFAM: helicase domain protein; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases. | DEAD/DEAH box helicase domain protein; DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation. | 0.917 |
Swoo_2292 | mutL | Swoo_2292 | Swoo_4172 | ATP-dependent DNA helicase, RecQ family; KEGG: sse:Ssed_2318 23S rRNA (Gm2251)-methyltransferase; TIGRFAM: ATP-dependent DNA helicase, RecQ family; PFAM: helicase domain protein; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases. | DNA mismatch repair protein MutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. | 0.793 |
Swoo_2292 | polA | Swoo_2292 | Swoo_0060 | ATP-dependent DNA helicase, RecQ family; KEGG: sse:Ssed_2318 23S rRNA (Gm2251)-methyltransferase; TIGRFAM: ATP-dependent DNA helicase, RecQ family; PFAM: helicase domain protein; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.891 |
Swoo_2292 | recA | Swoo_2292 | Swoo_3340 | ATP-dependent DNA helicase, RecQ family; KEGG: sse:Ssed_2318 23S rRNA (Gm2251)-methyltransferase; TIGRFAM: ATP-dependent DNA helicase, RecQ family; PFAM: helicase domain protein; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases. | recA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.867 |
Swoo_2292 | sbcD | Swoo_2292 | Swoo_3061 | ATP-dependent DNA helicase, RecQ family; KEGG: sse:Ssed_2318 23S rRNA (Gm2251)-methyltransferase; TIGRFAM: ATP-dependent DNA helicase, RecQ family; PFAM: helicase domain protein; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases. | Nuclease SbcCD, D subunit; SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity; Belongs to the SbcD family. | 0.815 |
Swoo_2292 | topA | Swoo_2292 | Swoo_1803 | ATP-dependent DNA helicase, RecQ family; KEGG: sse:Ssed_2318 23S rRNA (Gm2251)-methyltransferase; TIGRFAM: ATP-dependent DNA helicase, RecQ family; PFAM: helicase domain protein; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.935 |
Swoo_2292 | topB | Swoo_2292 | Swoo_2976 | ATP-dependent DNA helicase, RecQ family; KEGG: sse:Ssed_2318 23S rRNA (Gm2251)-methyltransferase; TIGRFAM: ATP-dependent DNA helicase, RecQ family; PFAM: helicase domain protein; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases. | DNA topoisomerase III; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA su [...] | 0.946 |
Swoo_2292 | xni | Swoo_2292 | Swoo_3460 | ATP-dependent DNA helicase, RecQ family; KEGG: sse:Ssed_2318 23S rRNA (Gm2251)-methyltransferase; TIGRFAM: ATP-dependent DNA helicase, RecQ family; PFAM: helicase domain protein; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases. | 5'-3' exonuclease; Has flap endonuclease activity. During DNA replication, flap endonucleases cleave the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. | 0.815 |
Swoo_4552 | Swoo_1374 | Swoo_4552 | Swoo_1374 | KEGG: sse:Ssed_0391 ATP-dependent DNA helicase RecQ; TIGRFAM: ATP-dependent DNA helicase, RecQ family; ATP-dependent DNA helicase RecQ; PFAM: helicase domain protein; HRDC domain protein; DEAD/DEAH box helicase domain protein; Helicase superfamily 1 and 2 ATP-binding; SMART: DEAD-like helicases. | PFAM: metallophosphoesterase; KEGG: sse:Ssed_1269 metallophosphoesterase. | 0.814 |
Swoo_4552 | Swoo_2292 | Swoo_4552 | Swoo_2292 | KEGG: sse:Ssed_0391 ATP-dependent DNA helicase RecQ; TIGRFAM: ATP-dependent DNA helicase, RecQ family; ATP-dependent DNA helicase RecQ; PFAM: helicase domain protein; HRDC domain protein; DEAD/DEAH box helicase domain protein; Helicase superfamily 1 and 2 ATP-binding; SMART: DEAD-like helicases. | ATP-dependent DNA helicase, RecQ family; KEGG: sse:Ssed_2318 23S rRNA (Gm2251)-methyltransferase; TIGRFAM: ATP-dependent DNA helicase, RecQ family; PFAM: helicase domain protein; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases. | 0.920 |
Swoo_4552 | deaD | Swoo_4552 | Swoo_0636 | KEGG: sse:Ssed_0391 ATP-dependent DNA helicase RecQ; TIGRFAM: ATP-dependent DNA helicase, RecQ family; ATP-dependent DNA helicase RecQ; PFAM: helicase domain protein; HRDC domain protein; DEAD/DEAH box helicase domain protein; Helicase superfamily 1 and 2 ATP-binding; SMART: DEAD-like helicases. | DEAD/DEAH box helicase domain protein; DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation. | 0.913 |