Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
msrBTIGRFAM: methionine-R-sulfoxide reductase; PFAM: Methionine sulfoxide reductase B; KEGG: sil:SPO3741 methionine sulfoxide reductase B. (148 aa)    
Predicted Functional Partners:
msrA
Peptide methionine sulfoxide reductase; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
 
 0.988
msrA-2
Peptide methionine sulfoxide reductase; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
 
 0.988
Swoo_2297
PFAM: protein of unknown function DUF1315; KEGG: sse:Ssed_2313 protein of unknown function DUF1315.
  
    0.938
Swoo_3005
PFAM: cytochrome c biogenesis protein transmembrane region; KEGG: sse:Ssed_3550 putative suppressor for copper-sensitivity B precursor.
   
 
 0.732
dsbD
Protein-disulfide reductase; Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps. Belongs to the thioredoxin family. DsbD subfamily.
   
 
 0.710
Swoo_0826
PFAM: Methionine sulfoxide reductase A; KEGG: shn:Shewana3_4324 methionine sulfoxide reductase A.
 
 
 0.707
Swoo_2443
PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; pyridine nucleotide-disulphide oxidoreductase dimerisation region; KEGG: sme:SMb21143 mercuric reductase.
  
  
 0.633
Swoo_2442
PFAM: protein of unknown function DUF427; KEGG: ava:Ava_2662 protein of unknown function DUF427.
       0.605
Swoo_2440
Hypothetical protein; KEGG: pha:PSHAa2959 oxidoreductase.
       0.596
grpE
GrpE protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...]
   
 
 0.593
Your Current Organism:
Shewanella woodyi
NCBI taxonomy Id: 392500
Other names: S. woodyi ATCC 51908, Shewanella woodyi ATCC 51908, Shewanella woodyi str. ATCC 51908, Shewanella woodyi strain ATCC 51908
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