Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Swoo_2550PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: sse:Ssed_2050 pyridoxal-5'-phosphate-dependent enzyme, beta subunit. (353 aa)    
Predicted Functional Partners:
Swoo_0622
O-succinylhomoserine (thiol)-lyase; KEGG: sse:Ssed_4041 cystathionine gamma-synthase; TIGRFAM: O-succinylhomoserine (thiol)-lyase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein.
 
 0.971
Swoo_0438
KEGG: sse:Ssed_4170 serine O-acetyltransferase; TIGRFAM: serine O-acetyltransferase; PFAM: transferase hexapeptide repeat containing protein; serine acetyltransferase domain protein.
  
 0.970
Swoo_1774
TIGRFAM: serine O-acetyltransferase; KEGG: sse:Ssed_2873 serine O-acetyltransferase.
  
 0.970
Swoo_2120
TIGRFAM: cystathionine beta-lyase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein; KEGG: sse:Ssed_2496 cystathionine beta-lyase.
  
 0.965
Swoo_0776
Sulfite reductase (NADPH) flavoprotein, alpha chain; Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH -> FAD -> FMN to the hemoprotein component.
  
 
 0.962
cysI
Sulfite reductase (NADPH) hemoprotein, beta-component; Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.
  
 
 0.962
Swoo_3095
Methionine gamma-lyase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein; aromatic amino acid beta-eliminating lyase/threonine aldolase; KEGG: sse:Ssed_1559 methionine gamma-lyase.
  
 0.930
serC
Phosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
    
 0.913
Swoo_2308
Aspartate transaminase; PFAM: aminotransferase class I and II; KEGG: sse:Ssed_2301 aspartate transaminase.
   
 0.906
Swoo_2857
TIGRFAM: cysteine synthase; cysteine synthase A; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: sse:Ssed_1721 cysteine synthase A; Belongs to the cysteine synthase/cystathionine beta- synthase family.
  
  
 
0.906
Your Current Organism:
Shewanella woodyi
NCBI taxonomy Id: 392500
Other names: S. woodyi ATCC 51908, Shewanella woodyi ATCC 51908, Shewanella woodyi str. ATCC 51908, Shewanella woodyi strain ATCC 51908
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