STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Swoo_2591KEGG: sse:Ssed_2014 phosphomethylpyrimidine kinase, thiamine-phosphate diphosphorylase; TIGRFAM: thiamine-phosphate pyrophosphorylase; phosphomethylpyrimidine kinase; PFAM: thiamine monophosphate synthase; Phosphomethylpyrimidine kinase type-1. (535 aa)    
Predicted Functional Partners:
thiC
Thiamine biosynthesis protein ThiC; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
 
 0.999
thiG
Thiazole biosynthesis family protein; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
 
 0.998
Swoo_2589
TIGRFAM: thiamine biosynthesis protein ThiS; PFAM: thiamineS protein; KEGG: sse:Ssed_2016 thiamine biosynthesis protein ThiS.
  
  
 0.989
Swoo_2587
TIGRFAM: thiazole biosynthesis protein ThiH; PFAM: Radical SAM domain protein; biotin and thiamin synthesis associated; KEGG: sse:Ssed_2018 thiazole biosynthesis protein ThiH.
 
  
 0.988
Swoo_2590
PFAM: UBA/THIF-type NAD/FAD binding protein; MoeZ/MoeB domain protein; KEGG: sse:Ssed_2015 UBA/ThiF-type NAD/FAD binding protein.
 
  
 0.985
thiL
Thiamine-monophosphate kinase; Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1; Belongs to the thiamine-monophosphate kinase family.
 
  
 0.956
Swoo_4770
TIGRFAM: molybdopterin synthase sulfurylase MoeB; PFAM: UBA/THIF-type NAD/FAD binding protein; MoeZ/MoeB domain protein; KEGG: sse:Ssed_4378 molybdopterin synthase sulfurylase MoeB.
 
  
 0.937
rsgA
Ribosome small subunit-dependent GTPase A; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit; Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
    
 0.922
Swoo_1207
PFAM: Alkaline phosphatase; KEGG: spl:Spea_0989 alkaline phosphatase; Belongs to the alkaline phosphatase family.
    
 0.908
Swoo_1349
PFAM: Alkaline phosphatase; KEGG: sse:Ssed_1249 alkaline phosphatase; Belongs to the alkaline phosphatase family.
    
 0.908
Your Current Organism:
Shewanella woodyi
NCBI taxonomy Id: 392500
Other names: S. woodyi ATCC 51908, Shewanella woodyi ATCC 51908, Shewanella woodyi str. ATCC 51908, Shewanella woodyi strain ATCC 51908
Server load: low (22%) [HD]