STRINGSTRING
folD protein (Shewanella woodyi) - STRING interaction network
"folD" - Bifunctional protein FolD in Shewanella woodyi
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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folDBifunctional protein FolD; Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (286 aa)    
Predicted Functional Partners:
fhs
PFAM- formate-tetrahydrofolate ligase FTHFS; KEGG- sse-Ssed_0612 formate--tetrahydrofolate ligase; Belongs to the formate--tetrahydrofolate ligase family (570 aa)
 
 
  0.992
glyA
Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (418 aa)
 
 
  0.990
gcvT
Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine (364 aa)
   
 
  0.984
purH
Bifunctional purine biosynthesis protein PurH; KEGG- spl-Spea_0432 phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; TIGRFAM- phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; PFAM- MGS domain protein; AICARFT/IMPCHase bienzyme formylation region (535 aa)
 
  0.980
purN
Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate (214 aa)
 
 
  0.971
purU
Formyltetrahydrofolate deformylase; Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4) (277 aa)
 
 
  0.967
Swoo_0624
KEGG- sse-Ssed_4039 methylenetetrahydrofolate reductase (NAD(P)H); TIGRFAM- 5,10-methylenetetrahydrofolate reductase; PFAM- methylenetetrahydrofolate reductase (296 aa)
   
 
  0.955
fmt
Methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus (320 aa)
   
  0.952
Swoo_3984
PFAM- 5-formyltetrahydrofolate cyclo-ligase; KEGG- spl-Spea_3311 5-formyltetrahydrofolate cyclo-ligase; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family (207 aa)
   
 
  0.948
guaA
GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP (525 aa)
   
   
  0.934
Your Current Organism:
Shewanella woodyi
NCBI taxonomy Id: 392500
Other names: S. woodyi ATCC 51908, Shewanella woodyi, Shewanella woodyi ATCC 51908, Shewanella woodyi ATCC51908, Shewanella woodyi str. ATCC 51908, Shewanella woodyi strain ATCC 51908
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