Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Swoo_3197KEGG: sse:Ssed_1478 3-hydroxyisobutyrate dehydrogenase; TIGRFAM: 3-hydroxyisobutyrate dehydrogenase; PFAM: NADP oxidoreductase coenzyme F420-dependent; 6-phosphogluconate dehydrogenase NAD-binding; Belongs to the HIBADH-related family. (305 aa)    
Predicted Functional Partners:
Swoo_3198
PFAM: Enoyl-CoA hydratase/isomerase; KEGG: sse:Ssed_1477 enoyl-CoA hydratase/isomerase.
 
 0.997
Swoo_3199
PFAM: Enoyl-CoA hydratase/isomerase; KEGG: sse:Ssed_1476 enoyl-CoA hydratase/isomerase; Belongs to the enoyl-CoA hydratase/isomerase family.
  
  
 0.987
Swoo_3201
TIGRFAM: methylmalonate-semialdehyde dehydrogenase; PFAM: Aldehyde Dehydrogenase; KEGG: sse:Ssed_1474 methylmalonate-semialdehyde dehydrogenase.
 
 
 0.964
Swoo_1113
TIGRFAM: methylmalonate-semialdehyde dehydrogenase; PFAM: Aldehyde Dehydrogenase; KEGG: sse:Ssed_1043 methylmalonate-semialdehyde dehydrogenase.
 
 
 0.925
Swoo_1114
PFAM: aminotransferase class-III; KEGG: sse:Ssed_1044 beta-alanine--pyruvate transaminase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
     
  0.900
Swoo_3862
KEGG: slo:Shew_3172 4-aminobutyrate aminotransferase; TIGRFAM: 4-aminobutyrate aminotransferase; PFAM: aminotransferase class-III; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
     
  0.900
Swoo_0119
PFAM: Enoyl-CoA hydratase/isomerase; KEGG: cps:CPS_2528 enoyl-CoA hydratase/isomerase family protein; Belongs to the enoyl-CoA hydratase/isomerase family.
  
  
 0.895
acsA
acetate--CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.
  
 
 0.851
Swoo_2498
KEGG: sse:Ssed_2112 2-methylcitrate synthase; TIGRFAM: 2-methylcitrate synthase/citrate synthase II; PFAM: Citrate synthase; Belongs to the citrate synthase family.
 
 
 0.848
Swoo_3221
PFAM: AMP-dependent synthetase and ligase; KEGG: sse:Ssed_1460 AMP-dependent synthetase and ligase.
  
 
 0.841
Your Current Organism:
Shewanella woodyi
NCBI taxonomy Id: 392500
Other names: S. woodyi ATCC 51908, Shewanella woodyi ATCC 51908, Shewanella woodyi str. ATCC 51908, Shewanella woodyi strain ATCC 51908
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