Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
Swoo_3266DNA polymerase III, alpha subunit; KEGG: sse:Ssed_3146 DNA-directed DNA polymerase; TIGRFAM: DNA polymerase III, alpha subunit; PFAM: PHP domain protein; nucleic acid binding OB-fold tRNA/helicase-type; DNA polymerase III alpha subunit; SMART: phosphoesterase PHP domain protein. (1157 aa)    
Predicted Functional Partners:
Swoo_0002
DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
  
 
 0.995
Swoo_1793
DNA polymerase III, subunits gamma and tau; KEGG: sse:Ssed_2852 DNA-directed DNA polymerase; TIGRFAM: DNA polymerase III, subunits gamma and tau; PFAM: AAA ATPase central domain protein; SMART: AAA ATPase.
 
 0.995
dnaQ
DNA polymerase III, epsilon subunit; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'- 5' exonuclease.
    
 0.994
Swoo_3704
DNA polymerase III, delta subunit; KEGG: sse:Ssed_3481 DNA-directed DNA polymerase; TIGRFAM: DNA polymerase III, delta subunit; PFAM: DNA polymerase III delta.
  
 0.992
Swoo_1983
TIGRFAM: DNA polymerase III, delta prime subunit; KEGG: sse:Ssed_2647 DNA-directed DNA polymerase.
    
 0.990
Swoo_1060
PFAM: DNA polymerase III chi subunit HolC; KEGG: sse:Ssed_1009 DNA polymerase III chi subunit, HolC.
   
 0.989
Swoo_2834
PFAM: Exonuclease RNase T and DNA polymerase III; SMART: Exonuclease; KEGG: slo:Shew_2368 exonuclease, RNase T and DNA polymerase III.
    
 0.968
Swoo_2197
DNA polymerase III, epsilon subunit; KEGG: sse:Ssed_2410 DNA-directed DNA polymerase; TIGRFAM: DNA polymerase III, epsilon subunit; PFAM: Exonuclease RNase T and DNA polymerase III; SMART: Exonuclease.
    
 0.927
Swoo_0640
Single-strand binding protein; Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.
 
 
 
 0.923
rpoB
DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
  
   
 0.874
Your Current Organism:
Shewanella woodyi
NCBI taxonomy Id: 392500
Other names: S. woodyi ATCC 51908, Shewanella woodyi ATCC 51908, Shewanella woodyi str. ATCC 51908, Shewanella woodyi strain ATCC 51908
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