Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Swoo_3290PFAM: protein of unknown function DUF446; KEGG: sse:Ssed_3170 hypothetical protein. (105 aa)    
Predicted Functional Partners:
Swoo_3289
PFAM: pseudouridine synthase; KEGG: sse:Ssed_3169 pseudouridylate synthase.
  
  
 0.855
Swoo_3291
KEGG: sse:Ssed_3171 hypothetical protein.
       0.660
Swoo_3292
KEGG: sse:Ssed_3172 hypothetical protein.
       0.540
Swoo_2785
PFAM: 37kDa nucleoid-associated protein; KEGG: sse:Ssed_1810 37 kDa nucleoid-associated protein.
  
     0.529
Swoo_0062
PFAM: Rhomboid family protein; KEGG: sse:Ssed_0098 rhomboid family protein.
  
     0.505
nfuA
IscR-regulated protein YhgI; Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins.
  
     0.473
Swoo_3120
PFAM: protein of unknown function DUF1282; KEGG: sse:Ssed_1534 protein of unknown function DUF1282.
  
     0.468
thiI
Thiamine biosynthesis/tRNA modification protein ThiI; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.
  
     0.444
rdgC
Putative exonuclease RdgC; May be involved in recombination; Belongs to the RdgC family.
  
   
 0.439
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
  
     0.408
Your Current Organism:
Shewanella woodyi
NCBI taxonomy Id: 392500
Other names: S. woodyi ATCC 51908, Shewanella woodyi ATCC 51908, Shewanella woodyi str. ATCC 51908, Shewanella woodyi strain ATCC 51908
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