Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Swoo_3439Transcriptional regulator, MerR family; PFAM: regulatory protein MerR; Transcription regulator MerR DNA binding; KEGG: bpd:BURPS668_0035 transcriptional regulator, MerR family. (136 aa)    
Predicted Functional Partners:
rpoD
RNA polymerase, sigma 70 subunit, RpoD; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.
  
 
 0.740
rpoB
DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.627
rpoC
DNA-directed RNA polymerase, beta' subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.624
rpoA
DNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
   0.620
rpoZ
DNA-directed RNA polymerase, omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
   
   0.617
Swoo_4718
PFAM: NUDIX hydrolase; KEGG: sse:Ssed_4346 NUDIX hydrolase.
   
    0.617
Swoo_3192
Transcriptional regulator, MerR family; PFAM: regulatory protein MerR; Transcription regulator MerR DNA binding; KEGG: sse:Ssed_1484 putative transcriptional regulator, MerR family.
  
     0.579
tpm
PFAM: thiopurine S-methyltransferase; KEGG: cps:CPS_3096 thiopurine S-methyltransferase family protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. TPMT family.
       0.518
Swoo_4123
PFAM: biotin/lipoyl attachment domain-containing protein; Carbamoyl-phosphate synthase L chain ATP-binding; Carbamoyl-phosphate synthetase large chain domain protein; biotin carboxylase domain protein; KEGG: sse:Ssed_3967 carbamoyl-phosphate synthase L chain, ATP-binding.
   
   0.478
Swoo_0587
PFAM: TonB-dependent receptor; TonB-dependent receptor plug; KEGG: noc:Noc_1820 TonB-dependent receptor.
  
     0.472
Your Current Organism:
Shewanella woodyi
NCBI taxonomy Id: 392500
Other names: S. woodyi ATCC 51908, Shewanella woodyi ATCC 51908, Shewanella woodyi str. ATCC 51908, Shewanella woodyi strain ATCC 51908
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