Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Swoo_3466PFAM: isocitrate/isopropylmalate dehydrogenase; KEGG: sse:Ssed_3318 isocitrate dehydrogenase (NAD(+)). (335 aa)    
Predicted Functional Partners:
Swoo_1837
2-oxoglutarate dehydrogenase, E1 subunit; KEGG: sse:Ssed_2814 oxoglutarate dehydrogenase (succinyl-transferring); TIGRFAM: 2-oxoglutarate dehydrogenase, E1 subunit; PFAM: dehydrogenase E1 component; Transketolase central region.
  
 0.940
Swoo_1221
PFAM: glutamine amidotransferase class-II; glutamate synthase alpha subunit domain protein; ferredoxin-dependent glutamate synthase; glutamate synthase; KEGG: sse:Ssed_1126 glutamate synthase (ferredoxin).
  
 
 0.930
leuC
3-isopropylmalate dehydratase, large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate.
 
 
 0.924
Swoo_1137
PFAM: pyruvate ferredoxin/flavodoxin oxidoreductase; pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; KEGG: sse:Ssed_1068 2-ketoglutarate: NADP oxidoreductase, alpha subunit.
     
 0.912
leuD
3-isopropylmalate dehydratase, small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily.
 
  
 0.908
Swoo_2702
Isocitrate dehydrogenase, NADP-dependent; KEGG: sse:Ssed_1883 isocitrate dehydrogenase (NADP(+)); TIGRFAM: isocitrate dehydrogenase, NADP-dependent; PFAM: Isocitrate dehydrogenase NADP-dependent monomeric type; Belongs to the monomeric-type IDH family.
    
 0.906
Swoo_0285
TIGRFAM: aconitate hydratase 2; PFAM: aconitate hydratase domain protein; Aconitase B, N-terminal; KEGG: sse:Ssed_0438 aconitate hydratase; Belongs to the aconitase/IPM isomerase family.
    
 0.905
Swoo_1138
PFAM: thiamine pyrophosphate protein domain protein TPP-binding; KEGG: sse:Ssed_1069 putative ferredoxin oxidoreductase beta subunit.
     
 0.903
argH
TIGRFAM: argininosuccinate lyase; PFAM: fumarate lyase; KEGG: sse:Ssed_4272 argininosuccinate lyase.
  
 
 0.837
Swoo_2267
PFAM: aminotransferase class I and II; KEGG: sse:Ssed_2340 aminotransferase, class I and II.
  
 0.837
Your Current Organism:
Shewanella woodyi
NCBI taxonomy Id: 392500
Other names: S. woodyi ATCC 51908, Shewanella woodyi ATCC 51908, Shewanella woodyi str. ATCC 51908, Shewanella woodyi strain ATCC 51908
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