| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Swoo_1159 | Swoo_1160 | Swoo_1159 | Swoo_1160 | Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | TIGRFAM: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase; PFAM: 78-dihydro-6-hydroxymethylpterin-pyrophosphokinase HPPK; KEGG: sse:Ssed_1079 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase. | 0.994 |
| Swoo_1159 | Swoo_1980 | Swoo_1159 | Swoo_1980 | Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | TIGRFAM: aminodeoxychorismate lyase; PFAM: aminotransferase class IV; KEGG: sse:Ssed_2650 aminotransferase, class IV. | 0.414 |
| Swoo_1159 | Swoo_2983 | Swoo_1159 | Swoo_2983 | Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | TIGRFAM: FolC bifunctional protein; PFAM: cytoplasmic peptidoglycan synthetase domain protein; Mur ligase middle domain protein; KEGG: sse:Ssed_1653 dihydrofolate synthase. | 0.625 |
| Swoo_1159 | Swoo_3567 | Swoo_1159 | Swoo_3567 | Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | 0.992 |
| Swoo_1159 | Swoo_3801 | Swoo_1159 | Swoo_3801 | Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | KEGG: sse:Ssed_3902 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase; TIGRFAM: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase; PFAM: 78-dihydro-6-hydroxymethylpterin-pyrophosphokinase HPPK. | 0.983 |
| Swoo_1159 | folE | Swoo_1159 | Swoo_4566 | Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | PFAM: GTP cyclohydrolase I; KEGG: spl:Spea_3842 GTP cyclohydrolase I. | 0.920 |
| Swoo_1159 | ftsH | Swoo_1159 | Swoo_3568 | Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | ATP-dependent metalloprotease FtsH; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. | 0.459 |
| Swoo_1160 | Swoo_1159 | Swoo_1160 | Swoo_1159 | TIGRFAM: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase; PFAM: 78-dihydro-6-hydroxymethylpterin-pyrophosphokinase HPPK; KEGG: sse:Ssed_1079 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase. | Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | 0.994 |
| Swoo_1160 | Swoo_1375 | Swoo_1160 | Swoo_1375 | TIGRFAM: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase; PFAM: 78-dihydro-6-hydroxymethylpterin-pyrophosphokinase HPPK; KEGG: sse:Ssed_1079 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase. | PFAM: beta-lactamase domain protein; KEGG: sus:Acid_3502 beta-lactamase domain protein. | 0.900 |
| Swoo_1160 | Swoo_2892 | Swoo_1160 | Swoo_2892 | TIGRFAM: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase; PFAM: 78-dihydro-6-hydroxymethylpterin-pyrophosphokinase HPPK; KEGG: sse:Ssed_1079 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase. | PFAM: dihydroneopterin aldolase; KEGG: spl:Spea_1664 dihydroneopterin aldolase. | 0.780 |
| Swoo_1160 | Swoo_2983 | Swoo_1160 | Swoo_2983 | TIGRFAM: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase; PFAM: 78-dihydro-6-hydroxymethylpterin-pyrophosphokinase HPPK; KEGG: sse:Ssed_1079 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase. | TIGRFAM: FolC bifunctional protein; PFAM: cytoplasmic peptidoglycan synthetase domain protein; Mur ligase middle domain protein; KEGG: sse:Ssed_1653 dihydrofolate synthase. | 0.587 |
| Swoo_1160 | Swoo_3567 | Swoo_1160 | Swoo_3567 | TIGRFAM: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase; PFAM: 78-dihydro-6-hydroxymethylpterin-pyrophosphokinase HPPK; KEGG: sse:Ssed_1079 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase. | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | 0.995 |
| Swoo_1160 | Swoo_3801 | Swoo_1160 | Swoo_3801 | TIGRFAM: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase; PFAM: 78-dihydro-6-hydroxymethylpterin-pyrophosphokinase HPPK; KEGG: sse:Ssed_1079 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase. | KEGG: sse:Ssed_3902 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase; TIGRFAM: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase; PFAM: 78-dihydro-6-hydroxymethylpterin-pyrophosphokinase HPPK. | 0.923 |
| Swoo_1160 | folE | Swoo_1160 | Swoo_4566 | TIGRFAM: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase; PFAM: 78-dihydro-6-hydroxymethylpterin-pyrophosphokinase HPPK; KEGG: sse:Ssed_1079 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase. | PFAM: GTP cyclohydrolase I; KEGG: spl:Spea_3842 GTP cyclohydrolase I. | 0.900 |
| Swoo_1160 | ftsH | Swoo_1160 | Swoo_3568 | TIGRFAM: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase; PFAM: 78-dihydro-6-hydroxymethylpterin-pyrophosphokinase HPPK; KEGG: sse:Ssed_1079 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase. | ATP-dependent metalloprotease FtsH; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. | 0.426 |
| Swoo_1160 | glmM | Swoo_1160 | Swoo_3566 | TIGRFAM: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase; PFAM: 78-dihydro-6-hydroxymethylpterin-pyrophosphokinase HPPK; KEGG: sse:Ssed_1079 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase. | Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family. | 0.406 |
| Swoo_1375 | Swoo_1160 | Swoo_1375 | Swoo_1160 | PFAM: beta-lactamase domain protein; KEGG: sus:Acid_3502 beta-lactamase domain protein. | TIGRFAM: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase; PFAM: 78-dihydro-6-hydroxymethylpterin-pyrophosphokinase HPPK; KEGG: sse:Ssed_1079 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase. | 0.900 |
| Swoo_1375 | Swoo_3567 | Swoo_1375 | Swoo_3567 | PFAM: beta-lactamase domain protein; KEGG: sus:Acid_3502 beta-lactamase domain protein. | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | 0.912 |
| Swoo_1375 | Swoo_3801 | Swoo_1375 | Swoo_3801 | PFAM: beta-lactamase domain protein; KEGG: sus:Acid_3502 beta-lactamase domain protein. | KEGG: sse:Ssed_3902 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase; TIGRFAM: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase; PFAM: 78-dihydro-6-hydroxymethylpterin-pyrophosphokinase HPPK. | 0.900 |
| Swoo_1980 | Swoo_1159 | Swoo_1980 | Swoo_1159 | TIGRFAM: aminodeoxychorismate lyase; PFAM: aminotransferase class IV; KEGG: sse:Ssed_2650 aminotransferase, class IV. | Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | 0.414 |