| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Swoo_3704 | Swoo_3712 | Swoo_3704 | Swoo_3712 | DNA polymerase III, delta subunit; KEGG: sse:Ssed_3481 DNA-directed DNA polymerase; TIGRFAM: DNA polymerase III, delta subunit; PFAM: DNA polymerase III delta. | Serine-type D-Ala-D-Ala carboxypeptidase; PFAM: peptidase S11 D-alanyl-D-alanine carboxypeptidase 1; Penicillin-binding protein 5 domain protein; KEGG: sse:Ssed_3489 serine-type D-Ala-D-Ala carboxypeptidase; Belongs to the peptidase S11 family. | 0.411 |
| Swoo_3704 | lptE | Swoo_3704 | Swoo_3703 | DNA polymerase III, delta subunit; KEGG: sse:Ssed_3481 DNA-directed DNA polymerase; TIGRFAM: DNA polymerase III, delta subunit; PFAM: DNA polymerase III delta. | Rare lipoprotein B; Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane. | 0.789 |
| Swoo_3704 | mrdA | Swoo_3704 | Swoo_3708 | DNA polymerase III, delta subunit; KEGG: sse:Ssed_3481 DNA-directed DNA polymerase; TIGRFAM: DNA polymerase III, delta subunit; PFAM: DNA polymerase III delta. | Penicillin-binding protein 2; Catalyzes cross-linking of the peptidoglycan cell wall. Belongs to the transpeptidase family. MrdA subfamily. | 0.538 |
| Swoo_3704 | mrdB | Swoo_3704 | Swoo_3709 | DNA polymerase III, delta subunit; KEGG: sse:Ssed_3481 DNA-directed DNA polymerase; TIGRFAM: DNA polymerase III, delta subunit; PFAM: DNA polymerase III delta. | Rod shape-determining protein RodA; Peptidoglycan polymerase that is essential for cell wall elongation; Belongs to the SEDS family. MrdB/RodA subfamily. | 0.521 |
| Swoo_3704 | nadD | Swoo_3704 | Swoo_3705 | DNA polymerase III, delta subunit; KEGG: sse:Ssed_3481 DNA-directed DNA polymerase; TIGRFAM: DNA polymerase III, delta subunit; PFAM: DNA polymerase III delta. | Nicotinate (nicotinamide) nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.852 |
| Swoo_3704 | rlmH | Swoo_3704 | Swoo_3707 | DNA polymerase III, delta subunit; KEGG: sse:Ssed_3481 DNA-directed DNA polymerase; TIGRFAM: DNA polymerase III, delta subunit; PFAM: DNA polymerase III delta. | Protein of unknown function DUF163; Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA; Belongs to the RNA methyltransferase RlmH family. | 0.633 |
| Swoo_3704 | rlpA | Swoo_3704 | Swoo_3711 | DNA polymerase III, delta subunit; KEGG: sse:Ssed_3481 DNA-directed DNA polymerase; TIGRFAM: DNA polymerase III, delta subunit; PFAM: DNA polymerase III delta. | Rare lipoprotein A; Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides. | 0.449 |
| Swoo_3704 | rsfS | Swoo_3704 | Swoo_3706 | DNA polymerase III, delta subunit; KEGG: sse:Ssed_3481 DNA-directed DNA polymerase; TIGRFAM: DNA polymerase III, delta subunit; PFAM: DNA polymerase III delta. | Iojap-like protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation. | 0.633 |
| Swoo_3712 | Swoo_3704 | Swoo_3712 | Swoo_3704 | Serine-type D-Ala-D-Ala carboxypeptidase; PFAM: peptidase S11 D-alanyl-D-alanine carboxypeptidase 1; Penicillin-binding protein 5 domain protein; KEGG: sse:Ssed_3489 serine-type D-Ala-D-Ala carboxypeptidase; Belongs to the peptidase S11 family. | DNA polymerase III, delta subunit; KEGG: sse:Ssed_3481 DNA-directed DNA polymerase; TIGRFAM: DNA polymerase III, delta subunit; PFAM: DNA polymerase III delta. | 0.411 |
| Swoo_3712 | lptE | Swoo_3712 | Swoo_3703 | Serine-type D-Ala-D-Ala carboxypeptidase; PFAM: peptidase S11 D-alanyl-D-alanine carboxypeptidase 1; Penicillin-binding protein 5 domain protein; KEGG: sse:Ssed_3489 serine-type D-Ala-D-Ala carboxypeptidase; Belongs to the peptidase S11 family. | Rare lipoprotein B; Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane. | 0.481 |
| Swoo_3712 | mrdA | Swoo_3712 | Swoo_3708 | Serine-type D-Ala-D-Ala carboxypeptidase; PFAM: peptidase S11 D-alanyl-D-alanine carboxypeptidase 1; Penicillin-binding protein 5 domain protein; KEGG: sse:Ssed_3489 serine-type D-Ala-D-Ala carboxypeptidase; Belongs to the peptidase S11 family. | Penicillin-binding protein 2; Catalyzes cross-linking of the peptidoglycan cell wall. Belongs to the transpeptidase family. MrdA subfamily. | 0.971 |
| Swoo_3712 | mrdB | Swoo_3712 | Swoo_3709 | Serine-type D-Ala-D-Ala carboxypeptidase; PFAM: peptidase S11 D-alanyl-D-alanine carboxypeptidase 1; Penicillin-binding protein 5 domain protein; KEGG: sse:Ssed_3489 serine-type D-Ala-D-Ala carboxypeptidase; Belongs to the peptidase S11 family. | Rod shape-determining protein RodA; Peptidoglycan polymerase that is essential for cell wall elongation; Belongs to the SEDS family. MrdB/RodA subfamily. | 0.708 |
| Swoo_3712 | nadD | Swoo_3712 | Swoo_3705 | Serine-type D-Ala-D-Ala carboxypeptidase; PFAM: peptidase S11 D-alanyl-D-alanine carboxypeptidase 1; Penicillin-binding protein 5 domain protein; KEGG: sse:Ssed_3489 serine-type D-Ala-D-Ala carboxypeptidase; Belongs to the peptidase S11 family. | Nicotinate (nicotinamide) nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.412 |
| Swoo_3712 | rlmH | Swoo_3712 | Swoo_3707 | Serine-type D-Ala-D-Ala carboxypeptidase; PFAM: peptidase S11 D-alanyl-D-alanine carboxypeptidase 1; Penicillin-binding protein 5 domain protein; KEGG: sse:Ssed_3489 serine-type D-Ala-D-Ala carboxypeptidase; Belongs to the peptidase S11 family. | Protein of unknown function DUF163; Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA; Belongs to the RNA methyltransferase RlmH family. | 0.653 |
| Swoo_3712 | rlpA | Swoo_3712 | Swoo_3711 | Serine-type D-Ala-D-Ala carboxypeptidase; PFAM: peptidase S11 D-alanyl-D-alanine carboxypeptidase 1; Penicillin-binding protein 5 domain protein; KEGG: sse:Ssed_3489 serine-type D-Ala-D-Ala carboxypeptidase; Belongs to the peptidase S11 family. | Rare lipoprotein A; Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides. | 0.721 |
| Swoo_3712 | rsfS | Swoo_3712 | Swoo_3706 | Serine-type D-Ala-D-Ala carboxypeptidase; PFAM: peptidase S11 D-alanyl-D-alanine carboxypeptidase 1; Penicillin-binding protein 5 domain protein; KEGG: sse:Ssed_3489 serine-type D-Ala-D-Ala carboxypeptidase; Belongs to the peptidase S11 family. | Iojap-like protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation. | 0.471 |
| engB | rlmH | Swoo_0058 | Swoo_3707 | GTP-binding protein HSR1-related; Necessary for normal cell division and for the maintenance of normal septation; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family. | Protein of unknown function DUF163; Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA; Belongs to the RNA methyltransferase RlmH family. | 0.612 |
| engB | rsfS | Swoo_0058 | Swoo_3706 | GTP-binding protein HSR1-related; Necessary for normal cell division and for the maintenance of normal septation; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family. | Iojap-like protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation. | 0.703 |
| lptE | Swoo_3704 | Swoo_3703 | Swoo_3704 | Rare lipoprotein B; Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane. | DNA polymerase III, delta subunit; KEGG: sse:Ssed_3481 DNA-directed DNA polymerase; TIGRFAM: DNA polymerase III, delta subunit; PFAM: DNA polymerase III delta. | 0.789 |
| lptE | Swoo_3712 | Swoo_3703 | Swoo_3712 | Rare lipoprotein B; Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane. | Serine-type D-Ala-D-Ala carboxypeptidase; PFAM: peptidase S11 D-alanyl-D-alanine carboxypeptidase 1; Penicillin-binding protein 5 domain protein; KEGG: sse:Ssed_3489 serine-type D-Ala-D-Ala carboxypeptidase; Belongs to the peptidase S11 family. | 0.481 |