Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Swoo_3726PFAM: ornithine cyclodeaminase/mu-crystallin; KEGG: spl:Spea_3170 ornithine cyclodeaminase. (318 aa)    
Predicted Functional Partners:
Swoo_2821
Proline racemase; Catalyzes the dehydration of trans-3-hydroxy-L-proline (t3LHyp) to Delta(1)-pyrroline-2-carboxylate (Pyr2C) in vitro. Displays no proline racemase activity.
 
  
 0.974
Swoo_0714
Delta-1-pyrroline-5-carboxylate dehydrogenase; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family.
  
 
 0.962
proC
Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
   
 
 0.924
Swoo_2262
KEGG: cps:CPS_0863 proline iminopeptidase; TIGRFAM: proline iminopeptidase; PFAM: alpha/beta hydrolase fold; Belongs to the peptidase S33 family.
     
  0.900
Swoo_4617
Prolyl aminopeptidase; PFAM: alpha/beta hydrolase fold; KEGG: sse:Ssed_0303 alpha/beta hydrolase fold; Belongs to the peptidase S33 family.
     
  0.900
Swoo_2823
PFAM: proline racemase; KEGG: sse:Ssed_1761 proline racemase; Belongs to the proline racemase family.
 
   
 0.678
Swoo_3727
RNA polymerase, sigma-24 subunit, ECF subfamily; TIGRFAM: RNA polymerase sigma factor, sigma-70 family; PFAM: sigma-70 region 2 domain protein; Sigma-70 region 4 type 2; KEGG: sse:Ssed_3504 RNA polymerase, sigma-24 subunit, ECF subfamily.
       0.456
Swoo_3728
KEGG: sse:Ssed_3505 hypothetical protein.
       0.456
Swoo_3729
KEGG: sse:Ssed_3506 hypothetical protein.
       0.456
Swoo_3725
PFAM: histidine kinase HAMP region domain protein; chemotaxis sensory transducer; KEGG: sse:Ssed_3502 methyl-accepting chemotaxis sensory transducer.
       0.433
Your Current Organism:
Shewanella woodyi
NCBI taxonomy Id: 392500
Other names: S. woodyi ATCC 51908, Shewanella woodyi ATCC 51908, Shewanella woodyi str. ATCC 51908, Shewanella woodyi strain ATCC 51908
Server load: low (12%) [HD]