STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Swoo_3835RNA polymerase, sigma-24 subunit, ECF subfamily; TIGRFAM: RNA polymerase sigma factor, sigma-70 family; PFAM: sigma-70 region 2 domain protein; sigma-70 region 4 domain protein; Sigma-70 region 4 type 2; KEGG: cps:CPS_0243 putative RNA polymerase sigma-70 factor FecI; Belongs to the sigma-70 factor family. ECF subfamily. (188 aa)    
Predicted Functional Partners:
Swoo_3834
anti-FecI sigma factor, FecR; PFAM: FecR protein; KEGG: cps:CPS_0244 putative regulatory protein.
 
 
 0.961
Swoo_1238
Anti sigma-E protein, RseA; An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish [...]
  
 
 0.867
Swoo_0701
anti-FecI sigma factor, FecR; PFAM: FecR protein; KEGG: cps:CPS_2817 putative regulatory protein.
 
 
 0.862
Swoo_3836
PFAM: TonB-dependent receptor; TonB-dependent receptor plug; KEGG: sde:Sde_2390 argininosuccinate synthase.
 
     0.787
Swoo_3838
PFAM: SapC family protein; KEGG: cps:CPS_0240 hypothetical protein.
 
     0.612
Swoo_3837
PFAM: tryptophan halogenase; KEGG: cps:CPS_0239 putative tryptophan halogenase.
 
     0.581
Swoo_3839
KEGG: cps:CPS_0241 hypothetical protein.
 
     0.561
Swoo_3833
PFAM: ROK family protein; KEGG: slo:Shew_1428 ROK family protein.
       0.450
Swoo_2684
TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; KEGG: saz:Sama_0619 response regulator receiver protein.
   
 
 0.431
Swoo_3316
KEGG: sse:Ssed_1338 hypothetical protein.
  
     0.425
Your Current Organism:
Shewanella woodyi
NCBI taxonomy Id: 392500
Other names: S. woodyi ATCC 51908, Shewanella woodyi ATCC 51908, Shewanella woodyi str. ATCC 51908, Shewanella woodyi strain ATCC 51908
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.