| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Swoo_2225 | nnrD | Swoo_2225 | Swoo_4175 | PFAM: NUDIX hydrolase; KEGG: sse:Ssed_2360 NUDIX hydrolase. | Carbohydrate kinase, YjeF related protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow t [...] | 0.888 |
| Swoo_3925 | groL | Swoo_3925 | Swoo_4308 | PFAM: NADH dehydrogenase (ubiquinone) 24 kDa subunit; Respiratory-chain NADH dehydrogenase domain 51 kDa subunit; KEGG: rde:RD1_4233 formate dehydrogenase, beta subunit. | Chaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.428 |
| Swoo_3925 | nnrD | Swoo_3925 | Swoo_4175 | PFAM: NADH dehydrogenase (ubiquinone) 24 kDa subunit; Respiratory-chain NADH dehydrogenase domain 51 kDa subunit; KEGG: rde:RD1_4233 formate dehydrogenase, beta subunit. | Carbohydrate kinase, YjeF related protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow t [...] | 0.836 |
| Swoo_3925 | nuoC | Swoo_3925 | Swoo_2862 | PFAM: NADH dehydrogenase (ubiquinone) 24 kDa subunit; Respiratory-chain NADH dehydrogenase domain 51 kDa subunit; KEGG: rde:RD1_4233 formate dehydrogenase, beta subunit. | NADH dehydrogenase I, D subunit; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; In the N-terminal section; belongs to the complex I 30 kDa subunit family. | 0.999 |
| Swoo_4173 | Swoo_4174 | Swoo_4173 | Swoo_4174 | N-acetylmuramoyl-L-alanine amidase; PFAM: Peptidoglycan-binding LysM; cell wall hydrolase/autolysin; KEGG: sse:Ssed_0794 N-acetylmuramoyl-L-alanine amidase. | PFAM: protein of unknown function UPF0079; KEGG: sse:Ssed_0793 protein of unknown function UPF0079. | 0.867 |
| Swoo_4173 | mutL | Swoo_4173 | Swoo_4172 | N-acetylmuramoyl-L-alanine amidase; PFAM: Peptidoglycan-binding LysM; cell wall hydrolase/autolysin; KEGG: sse:Ssed_0794 N-acetylmuramoyl-L-alanine amidase. | DNA mismatch repair protein MutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. | 0.797 |
| Swoo_4173 | nnrD | Swoo_4173 | Swoo_4175 | N-acetylmuramoyl-L-alanine amidase; PFAM: Peptidoglycan-binding LysM; cell wall hydrolase/autolysin; KEGG: sse:Ssed_0794 N-acetylmuramoyl-L-alanine amidase. | Carbohydrate kinase, YjeF related protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow t [...] | 0.836 |
| Swoo_4174 | Swoo_4173 | Swoo_4174 | Swoo_4173 | PFAM: protein of unknown function UPF0079; KEGG: sse:Ssed_0793 protein of unknown function UPF0079. | N-acetylmuramoyl-L-alanine amidase; PFAM: Peptidoglycan-binding LysM; cell wall hydrolase/autolysin; KEGG: sse:Ssed_0794 N-acetylmuramoyl-L-alanine amidase. | 0.867 |
| Swoo_4174 | mutL | Swoo_4174 | Swoo_4172 | PFAM: protein of unknown function UPF0079; KEGG: sse:Ssed_0793 protein of unknown function UPF0079. | DNA mismatch repair protein MutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. | 0.691 |
| Swoo_4174 | nnrD | Swoo_4174 | Swoo_4175 | PFAM: protein of unknown function UPF0079; KEGG: sse:Ssed_0793 protein of unknown function UPF0079. | Carbohydrate kinase, YjeF related protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow t [...] | 0.884 |
| Swoo_4194 | Swoo_4718 | Swoo_4194 | Swoo_4718 | ADP-ribose diphosphatase; PFAM: NUDIX hydrolase; KEGG: sse:Ssed_0775 ADP-ribose diphosphatase. | PFAM: NUDIX hydrolase; KEGG: sse:Ssed_4346 NUDIX hydrolase. | 0.912 |
| Swoo_4194 | nnrD | Swoo_4194 | Swoo_4175 | ADP-ribose diphosphatase; PFAM: NUDIX hydrolase; KEGG: sse:Ssed_0775 ADP-ribose diphosphatase. | Carbohydrate kinase, YjeF related protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow t [...] | 0.888 |
| Swoo_4718 | Swoo_4194 | Swoo_4718 | Swoo_4194 | PFAM: NUDIX hydrolase; KEGG: sse:Ssed_4346 NUDIX hydrolase. | ADP-ribose diphosphatase; PFAM: NUDIX hydrolase; KEGG: sse:Ssed_0775 ADP-ribose diphosphatase. | 0.912 |
| Swoo_4718 | nnrD | Swoo_4718 | Swoo_4175 | PFAM: NUDIX hydrolase; KEGG: sse:Ssed_4346 NUDIX hydrolase. | Carbohydrate kinase, YjeF related protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow t [...] | 0.888 |
| groL | Swoo_3925 | Swoo_4308 | Swoo_3925 | Chaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | PFAM: NADH dehydrogenase (ubiquinone) 24 kDa subunit; Respiratory-chain NADH dehydrogenase domain 51 kDa subunit; KEGG: rde:RD1_4233 formate dehydrogenase, beta subunit. | 0.428 |
| groL | mutL | Swoo_4308 | Swoo_4172 | Chaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | DNA mismatch repair protein MutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. | 0.491 |
| groL | nnrD | Swoo_4308 | Swoo_4175 | Chaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | Carbohydrate kinase, YjeF related protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow t [...] | 0.741 |
| groL | nuoC | Swoo_4308 | Swoo_2862 | Chaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | NADH dehydrogenase I, D subunit; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; In the N-terminal section; belongs to the complex I 30 kDa subunit family. | 0.606 |
| mutL | Swoo_4173 | Swoo_4172 | Swoo_4173 | DNA mismatch repair protein MutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. | N-acetylmuramoyl-L-alanine amidase; PFAM: Peptidoglycan-binding LysM; cell wall hydrolase/autolysin; KEGG: sse:Ssed_0794 N-acetylmuramoyl-L-alanine amidase. | 0.797 |
| mutL | Swoo_4174 | Swoo_4172 | Swoo_4174 | DNA mismatch repair protein MutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. | PFAM: protein of unknown function UPF0079; KEGG: sse:Ssed_0793 protein of unknown function UPF0079. | 0.691 |