Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Swoo_4193PFAM: protein of unknown function DUF1249; KEGG: sse:Ssed_0776 protein of unknown function DUF1249. (150 aa)    
Predicted Functional Partners:
Swoo_4194
ADP-ribose diphosphatase; PFAM: NUDIX hydrolase; KEGG: sse:Ssed_0775 ADP-ribose diphosphatase.
 
  
 0.907
cpdA
Calcineurin phosphoesterase domain protein; Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes.
 
  
 0.896
Swoo_4191
PFAM: protein of unknown function UPF0227; KEGG: sse:Ssed_0778 protein of unknown function UPF0227.
 
     0.671
Swoo_3047
KEGG: sse:Ssed_1602 hypothetical protein.
  
     0.646
rmf
Ribosome modulation factor; During stationary phase, converts 70S ribosomes to an inactive dimeric form (100S ribosomes); Belongs to the ribosome modulation factor family.
  
     0.578
slmA
Transcriptional regulator, TetR family; Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions.
  
     0.577
parE
DNA topoisomerase IV, B subunit; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase family. ParE type 1 subfamily.
       0.538
Swoo_0715
PFAM: SH3 type 3 domain protein; SMART: SH3 domain protein; KEGG: sse:Ssed_3845 SH3 domain protein.
  
    0.529
Swoo_3120
PFAM: protein of unknown function DUF1282; KEGG: sse:Ssed_1534 protein of unknown function DUF1282.
  
     0.515
Swoo_4195
TIGRFAM: type I secretion outer membrane protein, TolC family; PFAM: outer membrane efflux protein; KEGG: sse:Ssed_0774 type I secretion outer membrane protein, TolC family.
       0.513
Your Current Organism:
Shewanella woodyi
NCBI taxonomy Id: 392500
Other names: S. woodyi ATCC 51908, Shewanella woodyi ATCC 51908, Shewanella woodyi str. ATCC 51908, Shewanella woodyi strain ATCC 51908
Server load: medium (42%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.