Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Swoo_4527KEGG: spl:Spea_3805 conserved hypothetical protein. (150 aa)    
Predicted Functional Partners:
Swoo_4207
Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. Belongs to the helicase family. DnaB subfamily.
    
   0.832
priB
Single-strand binding protein/Primosomal replication protein n; Binds single-stranded DNA at the primosome assembly site (PAS); Belongs to the PriB family.
  
     0.659
Swoo_4526
PFAM: peptidase M23B; KEGG: sse:Ssed_0417 peptidase M23B.
       0.622
secA
Preprotein translocase, SecA subunit; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane. Belongs to the SecA family.
       0.570
Swoo_0342
PFAM: Sporulation domain protein; KEGG: sse:Ssed_4263 sporulation domain protein.
  
     0.531
Swoo_3084
PFAM: porin Gram-negative type; KEGG: sse:Ssed_2557 porin, gram-negative type.
  
     0.487
Swoo_4467
Transcriptional regulator, CadC; PFAM: transcriptional regulator domain protein; KEGG: spl:Spea_0489 transcriptional regulator, CadC.
  
     0.471
Swoo_2888
KEGG: sse:Ssed_1703 hypothetical protein.
  
     0.430
Swoo_4131
KEGG: sse:Ssed_3969 hypothetical protein.
  
     0.430
Swoo_3089
KEGG: sse:Ssed_1563 hypothetical protein; Belongs to the UPF0319 family.
  
     0.418
Your Current Organism:
Shewanella woodyi
NCBI taxonomy Id: 392500
Other names: S. woodyi ATCC 51908, Shewanella woodyi ATCC 51908, Shewanella woodyi str. ATCC 51908, Shewanella woodyi strain ATCC 51908
Server load: low (28%) [HD]