Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
pckAPhosphoenolpyruvate carboxykinase (ATP); Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA. Belongs to the phosphoenolpyruvate carboxykinase (ATP) family. (513 aa)    
Predicted Functional Partners:
ppc
Phosphoenolpyruvate carboxylase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle; Belongs to the PEPCase type 1 family.
     
 0.953
Swoo_1740
Conserved carboxylase region; PFAM: biotin/lipoyl attachment domain-containing protein; pyruvate carboxyltransferase; Conserved carboxylase region; KEGG: pat:Patl_3012 oxaloacetate decarboxylase alpha subunit.
  
 
 0.949
Swoo_3336
KEGG: sse:Ssed_1321 oxaloacetate decarboxylase; TIGRFAM: oxaloacetate decarboxylase alpha subunit; PFAM: biotin/lipoyl attachment domain-containing protein; pyruvate carboxyltransferase; Conserved carboxylase region.
  
 
 0.949
Swoo_2715
Phosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family.
     
 0.945
Swoo_2541
KEGG: sse:Ssed_2068 pyruvate kinase; TIGRFAM: pyruvate kinase; PFAM: Pyruvate kinase barrel; Pyruvate kinase alpha/beta; Belongs to the pyruvate kinase family.
    
 0.944
eno
Phosphopyruvate hydratase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
  
 
 0.941
mdh
Malate dehydrogenase, NAD-dependent; Catalyzes the reversible oxidation of malate to oxaloacetate.
  
 
 0.931
Swoo_1178
TIGRFAM: aspartate ammonia-lyase; PFAM: fumarate lyase; KEGG: sse:Ssed_1091 aspartate ammonia-lyase.
  
 
 0.926
Swoo_1832
KEGG: sse:Ssed_2819 citrate (Si)-synthase; TIGRFAM: citrate synthase I; PFAM: Citrate synthase; Belongs to the citrate synthase family.
  
 
 0.921
Swoo_2498
KEGG: sse:Ssed_2112 2-methylcitrate synthase; TIGRFAM: 2-methylcitrate synthase/citrate synthase II; PFAM: Citrate synthase; Belongs to the citrate synthase family.
  
 
 0.918
Your Current Organism:
Shewanella woodyi
NCBI taxonomy Id: 392500
Other names: S. woodyi ATCC 51908, Shewanella woodyi ATCC 51908, Shewanella woodyi str. ATCC 51908, Shewanella woodyi strain ATCC 51908
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