STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Swoo_4773RNA polymerase, sigma-24 subunit, ECF subfamily; TIGRFAM: RNA polymerase sigma factor, sigma-70 family; PFAM: sigma-70 region 2 domain protein; Sigma-70 region 4 type 2; KEGG: sse:Ssed_4382 sigma-24 (FecI-like); Belongs to the sigma-70 factor family. ECF subfamily. (161 aa)    
Predicted Functional Partners:
Swoo_4774
KEGG: sse:Ssed_4383 hypothetical protein.
  
    0.796
Swoo_4772
KEGG: sse:Ssed_4381 hypothetical protein.
       0.795
Swoo_4776
KEGG: sse:Ssed_4385 hypothetical protein.
  
    0.786
Swoo_4775
PFAM: protein of unknown function DUF692; Xylose isomerase domain protein TIM barrel; KEGG: sse:Ssed_4384 hypothetical protein.
  
    0.784
Swoo_1238
Anti sigma-E protein, RseA; An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish [...]
  
 
 0.633
Swoo_1789
KEGG: sse:Ssed_2856 hypothetical protein.
 
    0.551
gltS-2
Sodium/glutamate symporter; Catalyzes the sodium-dependent transport of glutamate. Belongs to the glutamate:Na(+) symporter (ESS) (TC 2.A.27) family.
  
    0.456
Swoo_2684
TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; KEGG: saz:Sama_0619 response regulator receiver protein.
   
 
 0.431
Your Current Organism:
Shewanella woodyi
NCBI taxonomy Id: 392500
Other names: S. woodyi ATCC 51908, Shewanella woodyi ATCC 51908, Shewanella woodyi str. ATCC 51908, Shewanella woodyi strain ATCC 51908
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.