Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
hutUUrocanate hydratase; Catalyzes the conversion of urocanate to 4-imidazolone-5- propionate. (556 aa)    
Predicted Functional Partners:
hutH
KEGG: slo:Shew_3756 histidine ammonia-lyase; TIGRFAM: histidine ammonia-lyase; PFAM: phenylalanine/histidine ammonia-lyase; Belongs to the PAL/histidase family.
 
 0.999
hutI
KEGG: sse:Ssed_4449 imidazolonepropionase; TIGRFAM: imidazolonepropionase; PFAM: amidohydrolase; Amidohydrolase 3; Belongs to the metallo-dependent hydrolases superfamily. HutI family.
 
 
 0.997
Swoo_3913
PFAM: phenylalanine/histidine ammonia-lyase; KEGG: spl:Spea_3575 phenylalanine/histidine ammonia-lyase.
 
 
 0.994
Swoo_4602
PFAM: phenylalanine/histidine ammonia-lyase; KEGG: sse:Ssed_0319 histidine ammonia-lyase.
 
 0.993
Swoo_4839
Transcriptional regulator, histidine utilization repressor, GntR family; TIGRFAM: histidine utilization repressor; PFAM: regulatory protein GntR HTH; UbiC transcription regulator-associated domain protein; KEGG: sse:Ssed_4448 transcriptional regulator, histidine utilization repressor, GntR family.
 
  
 0.923
Swoo_3912
TIGRFAM: flavocytochrome c; PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein; FAD dependent oxidoreductase; FMN-binding domain protein; KEGG: spl:Spea_3574 flavocytochrome c.
     
 0.903
gcvP
Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family.
  
  
 0.728
Swoo_0015
Amidohydrolase; PFAM: peptidase S9B dipeptidylpeptidase IV domain protein; amidohydrolase; WD40 domain protein beta Propeller; KEGG: sse:Ssed_0018 amidohydrolase.
  
  
 0.641
Swoo_1186
PFAM: amidohydrolase; KEGG: hne:HNE_0404 amidohydrolase family protein.
  
  
 0.616
Swoo_2368
PFAM: amidohydrolase; Amidohydrolase 3; KEGG: sfr:Sfri_2093 amidohydrolase.
  
  
 0.616
Your Current Organism:
Shewanella woodyi
NCBI taxonomy Id: 392500
Other names: S. woodyi ATCC 51908, Shewanella woodyi ATCC 51908, Shewanella woodyi str. ATCC 51908, Shewanella woodyi strain ATCC 51908
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.