STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Swoo_4916PFAM: purine or other phosphorylase family 1; KEGG: spl:Spea_3850 purine or other phosphorylase family 1. (279 aa)    
Predicted Functional Partners:
luxS
Quorum-sensing autoinducer 2 (AI-2), LuxS; Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD). Belongs to the LuxS family.
 
 
 0.974
mtnN
Adenosylhomocysteine nucleosidase; Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'- methylthioribose and S-ribosylhomocysteine, respectively. Belongs to the PNP/UDP phosphorylase family. MtnN subfamily.
  
  
 
0.925
speE
Spermidine synthase; Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
     
 0.903
Swoo_4919
KEGG: mmw:Mmwyl1_4374 DNA-cytosine methyltransferase; TIGRFAM: DNA-cytosine methyltransferase; PFAM: C-5 cytosine-specific DNA methylase.
    
  0.902
Swoo_3037
PFAM: membrane protein involved in aromatic hydrocarbon degradation; KEGG: sse:Ssed_1618 membrane protein involved in aromatic hydrocarbon degradation.
   
  
 0.745
Swoo_0566
PFAM: aminotransferase class V; beta-lactamase domain protein; SMART: Rhodanese domain protein; KEGG: slo:Shew_3354 aminotransferase, class V.
  
  
 0.562
Swoo_4915
TIGRFAM: nucleoside transporter; PFAM: Na+ dependent nucleoside transporter; nucleoside recognition domain protein; Na+ dependent nucleoside transporter domain protein; KEGG: spl:Spea_3851 nucleoside transporter; Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family.
  
  
 0.540
Swoo_1878
PFAM: protein kinase; Protein phosphatase 2C-like; SMART: tyrosine protein kinase; protein phosphatase 2C domain protein; serine/threonine protein kinase; KEGG: sse:Ssed_2762 serine/threonine protein kinase.
  
    0.521
Swoo_2627
PFAM: Protein phosphatase 2C-like; SMART: protein phosphatase 2C domain protein; serine/threonine protein kinase; KEGG: sse:Ssed_1963 serine/threonine protein kinase.
  
    0.521
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
  
  
 0.504
Your Current Organism:
Shewanella woodyi
NCBI taxonomy Id: 392500
Other names: S. woodyi ATCC 51908, Shewanella woodyi ATCC 51908, Shewanella woodyi str. ATCC 51908, Shewanella woodyi strain ATCC 51908
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.