Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SKD01460.1Branched-chain amino acid aminotransferase. (279 aa)    
Predicted Functional Partners:
ilvD
Dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family.
  
 0.937
SKC97059.1
Aspartate kinase.
  
 
 0.931
leuA
2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
 
 0.930
SKD01649.1
Para-aminobenzoate synthetase component 1.
 
 
 0.914
SKD10301.1
Dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family.
  
 0.912
ilvA
L-threonine ammonia-lyase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.
  
 0.896
SKD08776.1
Dihydropteroate synthase.
 
 
 0.893
SKD06071.1
Anthranilate synthase component 2.
 
 
 0.883
SKD00187.1
Homoserine dehydrogenase.
 
 
 0.878
SKD06559.1
Pyruvate/2-oxoglutarate/acetoin dehydrogenase complex, dehydrogenase (E1) component.
  
 0.876
Your Current Organism:
Chitinophaga ginsengisegetis
NCBI taxonomy Id: 393003
Other names: C. ginsengisegetis, Chitinophaga ginsengisegetis Lee et al. 2007, DSM 18108, KCTC 12654, strain Gsoil 040
Server load: medium (42%) [HD]