| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| SKC99507.1 | SKC99646.1 | SAMN05660461_1505 | SAMN05660461_1547 | Pyruvate kinase; Belongs to the pyruvate kinase family. | Pyruvate dehydrogenase E1 component beta subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. | 0.843 |
| SKC99507.1 | SKD05814.1 | SAMN05660461_1505 | SAMN05660461_3202 | Pyruvate kinase; Belongs to the pyruvate kinase family. | Acetolactate synthase, large subunit. | 0.783 |
| SKC99507.1 | SKD06559.1 | SAMN05660461_1505 | SAMN05660461_3474 | Pyruvate kinase; Belongs to the pyruvate kinase family. | Pyruvate/2-oxoglutarate/acetoin dehydrogenase complex, dehydrogenase (E1) component. | 0.890 |
| SKC99507.1 | SKD06855.1 | SAMN05660461_1505 | SAMN05660461_3583 | Pyruvate kinase; Belongs to the pyruvate kinase family. | 2-oxoisovalerate dehydrogenase E1 component. | 0.887 |
| SKC99507.1 | SKD07635.1 | SAMN05660461_1505 | SAMN05660461_3736 | Pyruvate kinase; Belongs to the pyruvate kinase family. | Malate dehydrogenase (oxaloacetate-decarboxylating)(NADP+). | 0.933 |
| SKC99507.1 | SKD07730.1 | SAMN05660461_1505 | SAMN05660461_3784 | Pyruvate kinase; Belongs to the pyruvate kinase family. | 2-oxoglutarate ferredoxin oxidoreductase subunit alpha. | 0.901 |
| SKC99507.1 | SKD08203.1 | SAMN05660461_1505 | SAMN05660461_4155 | Pyruvate kinase; Belongs to the pyruvate kinase family. | 2-oxoisovalerate dehydrogenase E1 component. | 0.887 |
| SKC99507.1 | mdh | SAMN05660461_1505 | SAMN05660461_3465 | Pyruvate kinase; Belongs to the pyruvate kinase family. | Malate dehydrogenase (NAD); Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family. | 0.978 |
| SKC99507.1 | pckA | SAMN05660461_1505 | SAMN05660461_2146 | Pyruvate kinase; Belongs to the pyruvate kinase family. | Phosphoenolpyruvate carboxykinase (ATP); Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA. | 0.862 |
| SKC99646.1 | SKC99507.1 | SAMN05660461_1547 | SAMN05660461_1505 | Pyruvate dehydrogenase E1 component beta subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. | Pyruvate kinase; Belongs to the pyruvate kinase family. | 0.843 |
| SKC99646.1 | SKD05814.1 | SAMN05660461_1547 | SAMN05660461_3202 | Pyruvate dehydrogenase E1 component beta subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. | Acetolactate synthase, large subunit. | 0.747 |
| SKC99646.1 | SKD06559.1 | SAMN05660461_1547 | SAMN05660461_3474 | Pyruvate dehydrogenase E1 component beta subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. | Pyruvate/2-oxoglutarate/acetoin dehydrogenase complex, dehydrogenase (E1) component. | 0.973 |
| SKC99646.1 | SKD06855.1 | SAMN05660461_1547 | SAMN05660461_3583 | Pyruvate dehydrogenase E1 component beta subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. | 2-oxoisovalerate dehydrogenase E1 component. | 0.956 |
| SKC99646.1 | SKD07635.1 | SAMN05660461_1547 | SAMN05660461_3736 | Pyruvate dehydrogenase E1 component beta subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. | Malate dehydrogenase (oxaloacetate-decarboxylating)(NADP+). | 0.928 |
| SKC99646.1 | SKD07730.1 | SAMN05660461_1547 | SAMN05660461_3784 | Pyruvate dehydrogenase E1 component beta subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. | 2-oxoglutarate ferredoxin oxidoreductase subunit alpha. | 0.868 |
| SKC99646.1 | SKD08203.1 | SAMN05660461_1547 | SAMN05660461_4155 | Pyruvate dehydrogenase E1 component beta subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. | 2-oxoisovalerate dehydrogenase E1 component. | 0.954 |
| SKC99646.1 | mdh | SAMN05660461_1547 | SAMN05660461_3465 | Pyruvate dehydrogenase E1 component beta subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. | Malate dehydrogenase (NAD); Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family. | 0.857 |
| SKC99646.1 | pckA | SAMN05660461_1547 | SAMN05660461_2146 | Pyruvate dehydrogenase E1 component beta subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. | Phosphoenolpyruvate carboxykinase (ATP); Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA. | 0.857 |
| SKC99646.1 | sucC | SAMN05660461_1547 | SAMN05660461_1805 | Pyruvate dehydrogenase E1 component beta subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. | succinyl-CoA synthetase beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 0.429 |
| SKD05814.1 | SKC99507.1 | SAMN05660461_3202 | SAMN05660461_1505 | Acetolactate synthase, large subunit. | Pyruvate kinase; Belongs to the pyruvate kinase family. | 0.783 |