ptaA protein (Pestalotiopsis fici) - STRING interaction network

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ptaA

Non-reducing polyketide synthase ptaA; Non-reducing polyketide synthase; part of the gene cluster that mediates the biosynthesis of pestheic acid, a diphenyl ether which is a biosynthetic precursor of the unique chloropupukeananes. The biosynthesis initiates from condensation of acetate and malonate units catalyzed by the non-reducing PKS ptaA. As the ptaA protein is TE/CLC domain-deficient, hydrolysis and Claisen cyclization of the polyketide could be catalyzed by ptaB containing a beta-lactamase domain. The ptaB protein might hydrolyze the thioester bond between the ACP of ptaA and t [...] (1746 aa)

Predicted Functional Partners:

PFICI_03942

0.932

PFICI_08881

0.920

PFICI_12664

0.913

PFICI_07948

0.897

PFICI_00329

0.515

PFICI_09514

0.468

PFICI_02081

0.441

PFICI_05764

0.427

PFICI_03827

0.427

PFICI_11756

0.422

Your Current Organism:

Pestalotiopsis fici

NCBI taxonomy Id: 1229662
Other names: P. fici W106-1, Pestalotiopsis fici W106-1

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
PFICI_00329	ptaA	W3XMI9	A0A067XNI2	AMP-binding domain-containing protein.	Non-reducing polyketide synthase ptaA; Non-reducing polyketide synthase; part of the gene cluster that mediates the biosynthesis of pestheic acid, a diphenyl ether which is a biosynthetic precursor of the unique chloropupukeananes. The biosynthesis initiates from condensation of acetate and malonate units catalyzed by the non-reducing PKS ptaA. As the ptaA protein is TE/CLC domain-deficient, hydrolysis and Claisen cyclization of the polyketide could be catalyzed by ptaB containing a beta-lactamase domain. The ptaB protein might hydrolyze the thioester bond between the ACP of ptaA and t [...]	0.515
PFICI_02081	ptaA	W3XQE5	A0A067XNI2	Carrier domain-containing protein.	Non-reducing polyketide synthase ptaA; Non-reducing polyketide synthase; part of the gene cluster that mediates the biosynthesis of pestheic acid, a diphenyl ether which is a biosynthetic precursor of the unique chloropupukeananes. The biosynthesis initiates from condensation of acetate and malonate units catalyzed by the non-reducing PKS ptaA. As the ptaA protein is TE/CLC domain-deficient, hydrolysis and Claisen cyclization of the polyketide could be catalyzed by ptaB containing a beta-lactamase domain. The ptaB protein might hydrolyze the thioester bond between the ACP of ptaA and t [...]	0.441
PFICI_03827	PFICI_09514	W3XK15	W3X3E1	KR domain-containing protein.	Uncharacterized protein.	0.437
PFICI_03827	ptaA	W3XK15	A0A067XNI2	KR domain-containing protein.	Non-reducing polyketide synthase ptaA; Non-reducing polyketide synthase; part of the gene cluster that mediates the biosynthesis of pestheic acid, a diphenyl ether which is a biosynthetic precursor of the unique chloropupukeananes. The biosynthesis initiates from condensation of acetate and malonate units catalyzed by the non-reducing PKS ptaA. As the ptaA protein is TE/CLC domain-deficient, hydrolysis and Claisen cyclization of the polyketide could be catalyzed by ptaB containing a beta-lactamase domain. The ptaB protein might hydrolyze the thioester bond between the ACP of ptaA and t [...]	0.427
PFICI_03942	ptaA	W3XKC7	A0A067XNI2	PKS_ER domain-containing protein.	Non-reducing polyketide synthase ptaA; Non-reducing polyketide synthase; part of the gene cluster that mediates the biosynthesis of pestheic acid, a diphenyl ether which is a biosynthetic precursor of the unique chloropupukeananes. The biosynthesis initiates from condensation of acetate and malonate units catalyzed by the non-reducing PKS ptaA. As the ptaA protein is TE/CLC domain-deficient, hydrolysis and Claisen cyclization of the polyketide could be catalyzed by ptaB containing a beta-lactamase domain. The ptaB protein might hydrolyze the thioester bond between the ACP of ptaA and t [...]	0.932
PFICI_05764	ptaA	W3XCR1	A0A067XNI2	Uncharacterized protein.	Non-reducing polyketide synthase ptaA; Non-reducing polyketide synthase; part of the gene cluster that mediates the biosynthesis of pestheic acid, a diphenyl ether which is a biosynthetic precursor of the unique chloropupukeananes. The biosynthesis initiates from condensation of acetate and malonate units catalyzed by the non-reducing PKS ptaA. As the ptaA protein is TE/CLC domain-deficient, hydrolysis and Claisen cyclization of the polyketide could be catalyzed by ptaB containing a beta-lactamase domain. The ptaB protein might hydrolyze the thioester bond between the ACP of ptaA and t [...]	0.427
PFICI_07948	ptaA	W3X336	A0A067XNI2	Uncharacterized protein.	Non-reducing polyketide synthase ptaA; Non-reducing polyketide synthase; part of the gene cluster that mediates the biosynthesis of pestheic acid, a diphenyl ether which is a biosynthetic precursor of the unique chloropupukeananes. The biosynthesis initiates from condensation of acetate and malonate units catalyzed by the non-reducing PKS ptaA. As the ptaA protein is TE/CLC domain-deficient, hydrolysis and Claisen cyclization of the polyketide could be catalyzed by ptaB containing a beta-lactamase domain. The ptaB protein might hydrolyze the thioester bond between the ACP of ptaA and t [...]	0.897
PFICI_08881	ptaA	W3WYS6	A0A067XNI2	PKS_ER domain-containing protein.	Non-reducing polyketide synthase ptaA; Non-reducing polyketide synthase; part of the gene cluster that mediates the biosynthesis of pestheic acid, a diphenyl ether which is a biosynthetic precursor of the unique chloropupukeananes. The biosynthesis initiates from condensation of acetate and malonate units catalyzed by the non-reducing PKS ptaA. As the ptaA protein is TE/CLC domain-deficient, hydrolysis and Claisen cyclization of the polyketide could be catalyzed by ptaB containing a beta-lactamase domain. The ptaB protein might hydrolyze the thioester bond between the ACP of ptaA and t [...]	0.920
PFICI_09514	PFICI_03827	W3X3E1	W3XK15	Uncharacterized protein.	KR domain-containing protein.	0.437
PFICI_09514	PFICI_12664	W3X3E1	W3WPB8	Uncharacterized protein.	Carrier domain-containing protein.	0.428
PFICI_09514	ptaA	W3X3E1	A0A067XNI2	Uncharacterized protein.	Non-reducing polyketide synthase ptaA; Non-reducing polyketide synthase; part of the gene cluster that mediates the biosynthesis of pestheic acid, a diphenyl ether which is a biosynthetic precursor of the unique chloropupukeananes. The biosynthesis initiates from condensation of acetate and malonate units catalyzed by the non-reducing PKS ptaA. As the ptaA protein is TE/CLC domain-deficient, hydrolysis and Claisen cyclization of the polyketide could be catalyzed by ptaB containing a beta-lactamase domain. The ptaB protein might hydrolyze the thioester bond between the ACP of ptaA and t [...]	0.468
PFICI_11756	ptaA	W3WRA3	A0A067XNI2	L-aminoadipate-semialdehyde dehydrogenase large subunit.	Non-reducing polyketide synthase ptaA; Non-reducing polyketide synthase; part of the gene cluster that mediates the biosynthesis of pestheic acid, a diphenyl ether which is a biosynthetic precursor of the unique chloropupukeananes. The biosynthesis initiates from condensation of acetate and malonate units catalyzed by the non-reducing PKS ptaA. As the ptaA protein is TE/CLC domain-deficient, hydrolysis and Claisen cyclization of the polyketide could be catalyzed by ptaB containing a beta-lactamase domain. The ptaB protein might hydrolyze the thioester bond between the ACP of ptaA and t [...]	0.422
PFICI_12664	PFICI_09514	W3WPB8	W3X3E1	Carrier domain-containing protein.	Uncharacterized protein.	0.428
PFICI_12664	ptaA	W3WPB8	A0A067XNI2	Carrier domain-containing protein.	Non-reducing polyketide synthase ptaA; Non-reducing polyketide synthase; part of the gene cluster that mediates the biosynthesis of pestheic acid, a diphenyl ether which is a biosynthetic precursor of the unique chloropupukeananes. The biosynthesis initiates from condensation of acetate and malonate units catalyzed by the non-reducing PKS ptaA. As the ptaA protein is TE/CLC domain-deficient, hydrolysis and Claisen cyclization of the polyketide could be catalyzed by ptaB containing a beta-lactamase domain. The ptaB protein might hydrolyze the thioester bond between the ACP of ptaA and t [...]	0.913
ptaA	PFICI_00329	A0A067XNI2	W3XMI9	Non-reducing polyketide synthase ptaA; Non-reducing polyketide synthase; part of the gene cluster that mediates the biosynthesis of pestheic acid, a diphenyl ether which is a biosynthetic precursor of the unique chloropupukeananes. The biosynthesis initiates from condensation of acetate and malonate units catalyzed by the non-reducing PKS ptaA. As the ptaA protein is TE/CLC domain-deficient, hydrolysis and Claisen cyclization of the polyketide could be catalyzed by ptaB containing a beta-lactamase domain. The ptaB protein might hydrolyze the thioester bond between the ACP of ptaA and t [...]	AMP-binding domain-containing protein.	0.515
ptaA	PFICI_02081	A0A067XNI2	W3XQE5	Non-reducing polyketide synthase ptaA; Non-reducing polyketide synthase; part of the gene cluster that mediates the biosynthesis of pestheic acid, a diphenyl ether which is a biosynthetic precursor of the unique chloropupukeananes. The biosynthesis initiates from condensation of acetate and malonate units catalyzed by the non-reducing PKS ptaA. As the ptaA protein is TE/CLC domain-deficient, hydrolysis and Claisen cyclization of the polyketide could be catalyzed by ptaB containing a beta-lactamase domain. The ptaB protein might hydrolyze the thioester bond between the ACP of ptaA and t [...]	Carrier domain-containing protein.	0.441
ptaA	PFICI_03827	A0A067XNI2	W3XK15	Non-reducing polyketide synthase ptaA; Non-reducing polyketide synthase; part of the gene cluster that mediates the biosynthesis of pestheic acid, a diphenyl ether which is a biosynthetic precursor of the unique chloropupukeananes. The biosynthesis initiates from condensation of acetate and malonate units catalyzed by the non-reducing PKS ptaA. As the ptaA protein is TE/CLC domain-deficient, hydrolysis and Claisen cyclization of the polyketide could be catalyzed by ptaB containing a beta-lactamase domain. The ptaB protein might hydrolyze the thioester bond between the ACP of ptaA and t [...]	KR domain-containing protein.	0.427
ptaA	PFICI_03942	A0A067XNI2	W3XKC7	Non-reducing polyketide synthase ptaA; Non-reducing polyketide synthase; part of the gene cluster that mediates the biosynthesis of pestheic acid, a diphenyl ether which is a biosynthetic precursor of the unique chloropupukeananes. The biosynthesis initiates from condensation of acetate and malonate units catalyzed by the non-reducing PKS ptaA. As the ptaA protein is TE/CLC domain-deficient, hydrolysis and Claisen cyclization of the polyketide could be catalyzed by ptaB containing a beta-lactamase domain. The ptaB protein might hydrolyze the thioester bond between the ACP of ptaA and t [...]	PKS_ER domain-containing protein.	0.932
ptaA	PFICI_05764	A0A067XNI2	W3XCR1	Non-reducing polyketide synthase ptaA; Non-reducing polyketide synthase; part of the gene cluster that mediates the biosynthesis of pestheic acid, a diphenyl ether which is a biosynthetic precursor of the unique chloropupukeananes. The biosynthesis initiates from condensation of acetate and malonate units catalyzed by the non-reducing PKS ptaA. As the ptaA protein is TE/CLC domain-deficient, hydrolysis and Claisen cyclization of the polyketide could be catalyzed by ptaB containing a beta-lactamase domain. The ptaB protein might hydrolyze the thioester bond between the ACP of ptaA and t [...]	Uncharacterized protein.	0.427
ptaA	PFICI_07948	A0A067XNI2	W3X336	Non-reducing polyketide synthase ptaA; Non-reducing polyketide synthase; part of the gene cluster that mediates the biosynthesis of pestheic acid, a diphenyl ether which is a biosynthetic precursor of the unique chloropupukeananes. The biosynthesis initiates from condensation of acetate and malonate units catalyzed by the non-reducing PKS ptaA. As the ptaA protein is TE/CLC domain-deficient, hydrolysis and Claisen cyclization of the polyketide could be catalyzed by ptaB containing a beta-lactamase domain. The ptaB protein might hydrolyze the thioester bond between the ACP of ptaA and t [...]	Uncharacterized protein.	0.897

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