Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ABO_0017Secretion protein HlyD family; Family membership. (329 aa)    
Predicted Functional Partners:
ABO_0015
Conserved hypothetical protein; Putative inner membrane protein as shown by TMHMM hits.
 
  
 0.946
macB
ABC transporter, ATP-binding protein/permease, putative; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides.
  
  
 0.779
ABO_0014
Transcriptional regulator MarR family identified by sequencesimilarity; putative InterPro: Bacterial regulatory protein MarR family; Family membership.
  
  
 0.770
ABO_1135
Efflux transporter permease protein putative; Specificity unclear.
 
  
 0.770
ABO_0016
Conserved hypothetical protein; Identified by sequence similarity.
       0.754
ABO_0250
Outer membrane protein identified by sequence similarity; putative InterPro: Outer membrane efflux protein; Function unclear.
 
 
 0.693
ABO_0963
InterPro: Outer membrane efflux protein probably a component that vonfers multidrug resistance. could also be implicated in the secretion of the siderophore, pyoverdine. probably involved in the efflux of the siderophore across the outer membrane; Hypothetical protein.
 
 
 0.672
ABO_0965
(multidrug/solvent RND membrane fusion protein) identified by sequence similarity; putative InterPro: HlyD family secretion protein; High confidence in function and specificity; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
 
   
 0.487
ABO_0018
Hypothetical protein.
       0.473
ABO_0013
Conserved hypothetical protein.
       0.467
Your Current Organism:
Alcanivorax borkumensis
NCBI taxonomy Id: 393595
Other names: A. borkumensis SK2, Alcanivorax borkumensis SK2, Alcanivorax borkumensis str. SK2, Alcanivorax borkumensis strain SK2
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