Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
mmsRTranscriptional regulator (AraC family) identified by match to PFAM protein family HMMPF00165 InterPro: AraC type helix-turn-helix; High confidence in function and specificity. (305 aa)    
Predicted Functional Partners:
cobB
Identified by match to PFAM protein family HMMPF02146 InterPro: Sir2 family; High confidence in function and specificity; Belongs to the sirtuin family. Class III subfamily.
  
    0.633
mmsA
(methylmalonate semialdehyde dehydrogenase) identified by sequence similarity; putative InterPro: Aldehyde dehydrogenase family distal valine metabolic pathway; High confidence in function and specificity.
  
  
 0.594
gltB
Glutamate synthase, large subunit; Identified by sequencesimilarity; putative identified by match to PFAM protein family HMMPF04897 and HMMPF01645 InterPro: Ferredoxin-dependent glutamate synthase; High confidence in function and specificity.
     
 0.578
algA
(mannose-1-phosphateguanylyltransferase/mannose-6-p hosphate isomerase) identified by match to PFAM protein family HMMPF00483 InterPro: ADP-glucose pyrophosphorylase; High confidence in function and specificity; Belongs to the mannose-6-phosphate isomerase type 2 family.
  
 
 0.526
ABO_1784
Non-ribosomal peptide synthase fragment, contains condensation, fatty-acid-CoA ligase and thioesterase domains. identified by sequence similarity; putative InterPro: AMP-dependent synthetase and ligase; Family membership.
     
 0.516
ABO_0662
Conserved hypothetical protein.
 
    0.504
ABO_0832
Transcriptional regulator, AraC family; Identified by match to PFAM protein family HMMPF00165 InterPro: ThiJ/PfpI family; Specificity unclear.
 
 
0.498
rpoD
RNA polymerase sigma factor RpoD; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.
   
 
 0.485
rpoH
RNA polymerase sigma-32 factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes.
   
 
 0.485
ABO_1995
Transcriptional regulator, AraC family InterPro: AraC type helix-turn-helix HTH reporting nucleic acid binding motif; Family membership.
 
 
 0.478
Your Current Organism:
Alcanivorax borkumensis
NCBI taxonomy Id: 393595
Other names: A. borkumensis SK2, Alcanivorax borkumensis SK2, Alcanivorax borkumensis str. SK2, Alcanivorax borkumensis strain SK2
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