mmsA protein (Alcanivorax borkumensis) - STRING interaction network

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mmsA

(methylmalonate semialdehyde dehydrogenase) identified by sequence similarity; putative InterPro: Aldehyde dehydrogenase family distal valine metabolic pathway; High confidence in function and specificity. (499 aa)

Predicted Functional Partners:

mmsB

0.960

prpC

0.929

ABO_0509

0.926

mmsB-2

0.925

fadA1

0.924

fadA2

0.924

fadA3

0.924

alkH

0.924

aldh1

0.922

acsA

0.912

Your Current Organism:

Alcanivorax borkumensis

NCBI taxonomy Id: 393595
Other names: A. borkumensis SK2, Alcanivorax borkumensis SK2, Alcanivorax borkumensis str. SK2, Alcanivorax borkumensis strain SK2

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ABO_0509	aldh1	ABO_0509	ABO_0962	(aminotransferase, putative) identified by sequence similarity; putative identified by match to PFAM protein family HMMPF00202 InterPro: Aminotransferase class-III pyridoxal-phosphate; Specificity unclear; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.	Identified by match to TIGR protein family HMMTIGR01722 InterPro: Aldehyde dehydrogenase family; Specificity unclear.	0.925
ABO_0509	alkH	ABO_0509	ABO_2709	(aminotransferase, putative) identified by sequence similarity; putative identified by match to PFAM protein family HMMPF00202 InterPro: Aminotransferase class-III pyridoxal-phosphate; Specificity unclear; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.	(aldehyde dehydrogenase family protein) identified by match to TIGR protein family HMMTIGR01722 InterPro: Aldehyde dehydrogenase family; High confidence in function and specificity.	0.925
ABO_0509	mmsA	ABO_0509	ABO_0020	(aminotransferase, putative) identified by sequence similarity; putative identified by match to PFAM protein family HMMPF00202 InterPro: Aminotransferase class-III pyridoxal-phosphate; Specificity unclear; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.	(methylmalonate semialdehyde dehydrogenase) identified by sequence similarity; putative InterPro: Aldehyde dehydrogenase family distal valine metabolic pathway; High confidence in function and specificity.	0.926
acsA	aldh1	ABO_0334	ABO_0962	acetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.	Identified by match to TIGR protein family HMMTIGR01722 InterPro: Aldehyde dehydrogenase family; Specificity unclear.	0.912
acsA	alkH	ABO_0334	ABO_2709	acetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.	(aldehyde dehydrogenase family protein) identified by match to TIGR protein family HMMTIGR01722 InterPro: Aldehyde dehydrogenase family; High confidence in function and specificity.	0.912
acsA	fadA1	ABO_0334	ABO_0253	acetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.	acetyl-CoA acyltransferase; Identified by sequence similarity; High confidence in function and specificity; Belongs to the thiolase-like superfamily. Thiolase family.	0.914
acsA	fadA2	ABO_0334	ABO_1653	acetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.	3-oxoacyl-CoA thiolase; Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed.	0.829
acsA	fadA3	ABO_0334	ABO_2452	acetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.	3-ketoacyl-CoA thiolase; Identified by match to PFAM protein family HMMPF00108 InterPro: thiolase family protein; High confidence in function and specificity; Belongs to the thiolase-like superfamily. Thiolase family.	0.829
acsA	mmsA	ABO_0334	ABO_0020	acetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.	(methylmalonate semialdehyde dehydrogenase) identified by sequence similarity; putative InterPro: Aldehyde dehydrogenase family distal valine metabolic pathway; High confidence in function and specificity.	0.912
acsA	mmsB	ABO_0334	ABO_0022	acetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.	3-hydroxyisobutyrate dehydrogenase; Identified by sequence similarity; High confidence in function and specificity.	0.823
acsA	mmsB-2	ABO_0334	ABO_1503	acetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.	3-hydroxyisobutyrate dehydrogenase; Identified by sequencesimilarity; putative; Family membership.	0.804
acsA	prpC	ABO_0334	ABO_1432	acetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.	Methylcitrate synthase putative identified by sequence similarity; putative InterPro: Citrate synthase; High confidence in function and specificity; Belongs to the citrate synthase family.	0.926
aldh1	ABO_0509	ABO_0962	ABO_0509	Identified by match to TIGR protein family HMMTIGR01722 InterPro: Aldehyde dehydrogenase family; Specificity unclear.	(aminotransferase, putative) identified by sequence similarity; putative identified by match to PFAM protein family HMMPF00202 InterPro: Aminotransferase class-III pyridoxal-phosphate; Specificity unclear; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.	0.925
aldh1	acsA	ABO_0962	ABO_0334	Identified by match to TIGR protein family HMMTIGR01722 InterPro: Aldehyde dehydrogenase family; Specificity unclear.	acetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.	0.912
aldh1	alkH	ABO_0962	ABO_2709	Identified by match to TIGR protein family HMMTIGR01722 InterPro: Aldehyde dehydrogenase family; Specificity unclear.	(aldehyde dehydrogenase family protein) identified by match to TIGR protein family HMMTIGR01722 InterPro: Aldehyde dehydrogenase family; High confidence in function and specificity.	0.923
aldh1	mmsA	ABO_0962	ABO_0020	Identified by match to TIGR protein family HMMTIGR01722 InterPro: Aldehyde dehydrogenase family; Specificity unclear.	(methylmalonate semialdehyde dehydrogenase) identified by sequence similarity; putative InterPro: Aldehyde dehydrogenase family distal valine metabolic pathway; High confidence in function and specificity.	0.922
aldh1	mmsB	ABO_0962	ABO_0022	Identified by match to TIGR protein family HMMTIGR01722 InterPro: Aldehyde dehydrogenase family; Specificity unclear.	3-hydroxyisobutyrate dehydrogenase; Identified by sequence similarity; High confidence in function and specificity.	0.911
aldh1	mmsB-2	ABO_0962	ABO_1503	Identified by match to TIGR protein family HMMTIGR01722 InterPro: Aldehyde dehydrogenase family; Specificity unclear.	3-hydroxyisobutyrate dehydrogenase; Identified by sequencesimilarity; putative; Family membership.	0.908
aldh1	prpC	ABO_0962	ABO_1432	Identified by match to TIGR protein family HMMTIGR01722 InterPro: Aldehyde dehydrogenase family; Specificity unclear.	Methylcitrate synthase putative identified by sequence similarity; putative InterPro: Citrate synthase; High confidence in function and specificity; Belongs to the citrate synthase family.	0.859
alkH	ABO_0509	ABO_2709	ABO_0509	(aldehyde dehydrogenase family protein) identified by match to TIGR protein family HMMTIGR01722 InterPro: Aldehyde dehydrogenase family; High confidence in function and specificity.	(aminotransferase, putative) identified by sequence similarity; putative identified by match to PFAM protein family HMMPF00202 InterPro: Aminotransferase class-III pyridoxal-phosphate; Specificity unclear; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.	0.925

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